Hypertension Flashcards

1
Q

what is hypertension a risk factor for?

A
  • Cerebral Haemorrhage
  • Atheroma
  • Renal Failure
  • Sudden cardiac death
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2
Q

what is the formula for BP?

A

BP= CO+ TPR

blood pressure= cardiac output + total peripheral resistance

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3
Q

what does angiotensin 2 do?

A

stimulates release of aldosterone
causes vasoconstriction
increases blood pressure

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4
Q

what does aldosterone do?

A

causes salt and water retention by the kidneys

thus increasing the BP

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5
Q

what is primary hypertension?

A

idiopathic hypertension

no found underlying cause

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6
Q

how does increase of salt consumption increase the blood pressure?

A

it causes the stimulation of aldosterone which then causes retention of salt and water thus increasing the BP

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7
Q

what is secondary hypertension?

A

hypertension with a known underlying cause

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8
Q

what are the common underlying diseases that cause secondary hypertension?

A

renal disease/ renal artery stenosis
endocrine disease
drug therapy

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9
Q

what is Conn’s syndrome?

A

an excess amount of aldosterone, causing hypertension

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10
Q

what is Cushing’s syndrome?

A

an excess amount of corticosteroids causing hypertension

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11
Q

what is Pheochromocytoma?

A

a tumour which causes the overproduction of certain hormones eg noradrenaline (which causes increased BP)

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12
Q

what is Coarctation of the aorta?

A

congenital narrowing of segments of the aorta

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13
Q

what drug therapy can cause hypertension?

A

use of corticosteroids

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14
Q

what is benign hypertension?

A

hypertension that is Asymptomatic, still should be treated aggressively

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15
Q

what happens if benign hypertension remains untreated?

A

left ventricular hypertrophy, congestive cardiac failure, berry aneurysm, aortic dissection, renal disease

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16
Q

what are the effects of microvascular injury?

A

small arteries and arterioles have thickening of media (smooth muscle), hyaline arteriosclerosis (plasma proteins forced into vessel walls)

17
Q

What is malignant hypertension?

A

diastolic blood pressure above 130mmHg
also known as accelerated hypertension
usually includes grade 4 retinopathy

18
Q

what can malignant hypertension cause?

A
cerebral oedema (papilloedema), acute renal failure, acute heart failure, headache and cerebral haemorrhage
Blood vessels undergo fibrinoid necrosis and endarteritis proliferans
19
Q

how common is pregnancy associated hypertension?

A

10% of pregnancies