Hypersensitivity Reactions Flashcards
What type of hypersensitivity (I-V) is anaphylaxis?
Type I - IgE mediated
What type of hypersensitivity (I-V) is food allergy?
Type I - IgE mediated
What type of hypersensitivity (I-V) is allergic rhinitis?
Type I - IgE mediated
What type of hypersensitivity (I-V) is asthma?
Type I - IgE mediated
What type of hypersensitivity (I-V) is angioedema?
Type I - IgE mediated
What type of hypersensitivity (I-V) is Auto-immune haemolytic anaemia?
Type II
What type of hypersensitivity (I-V) is Goodpasture disease?
Type II - antibodies against the basement membrane’s collagen type IV
What type of hypersensitivity (I-V) is pemphigus vulgaris?
Type II - antibodies against epidermal cadherin
What type of hypersensitivity (I-V) is Graves disease?
Type II - antibodies against TSH receptor
What type of hypersensitivity (I-V) is Myasthenia Gravis?
Type II - antibodies against the ACh receptor
What type of hypersensitivity (I-V) is cryoglobulinaemia?
Type III immune-complex driven
What type of hypersensitivity (I-V) is SLE?
Type III immune-complex driven - nuclear antigens (DNA, histones, RNP)
What type of hypersensitivity (I-V) is Rheumatoid arthritis?
Type III immune-complex driven - Fc region of IgG
and
Type IV T-cell mediated (delayed) - unknown target
What type of hypersensitivity (I-V) is T1DM?
Type IV T-cell mediated (delayed) - pancreatic beta cell proteins
What type of hypersensitivity (I-V) is Multiple Sclerosis?
Type IV T-cell mediated (delayed) - Myelin Basic Protein