Hypersensitivity reactions

Question 1

Immune reactant: IgE

Antigen: soluble antigen

effector mechanism: Ag induces crosslinking of IgE bound to mast cells and basophils w/ release of vasoactive mediators (histamine)

example of hypersensitivity rxn: allergic rhinitis, asthma, systemic anaphylaxis, localized anaphylaxis, hay fever, food allergies, and eczema

What type of hypersensitivity is it?

Answer 1

Type I

Question 2

Which hypersensitivity type is an over-expression of cytokines leading to cell death?

A. Type I

B. Type II

C. Type III

D. Type IV

Answer 2

D. Type IV

Question 3

Which hypersensitivity type damages vessel lining?

A. Type I

B. Type II

C. Type III

D. Type IV

Answer 3

C. Type III

Question 4

Which hypersensitivity type is associated with IgE antibody?

A. Type I

B. Type II

C. Type III

D. Type IV

Answer 4

A. Type I