Common CD Markers

Question 0

Expressed on: CD4+ T cells and CD8+ T cells

Function: signal transduction element of TCR, it’s the hair extensions, it doesn’t bind antigen

Answer 0

CD3

Question 1

Expressed on: CD4+ T cells, CD8+ T cells, and NK cells

Function: adhesion and signal transduction

Answer 1

CD 2

Question 2

Expressed on: Th cells

Function: adhesion, it binds to MHC II (HLA-DR, DP, and DQ), signal transduction

Answer 2

CD4

Question 3

Expressed on: B cells, CD4+ T cells, and CD8+ T cells

Function: unknown

Answer 3

CD5

Question 4

Expressed on: cytotoxic T cells and some NK cells (variable)

Function: adhesion, it binds to MHC II (HLA-A,B, and C), and signal transduction

Answer 4

CD8

Question 5

Expressed on: NK cells

Function: low affinity receptor for Fc region of IgG

Answer 5

CD16 (Fc gamma RIII)

Question 6

Expressed on: B cells
Function: receptor for C3d (complement) and Epstein-Barr virus (EBV)
You must be 21 to sit at the bar

Answer 6

CD21(CR 2)

Question 7

Expressed on: CD4+ T cells and CD8+ T cells

Function: receptor for co-stimulatory B7 molecule on APCs

Answer 7

CD28

Question 8

Expressed on: B cells

Function: receptor for Fc region of IgG

Answer 8

CD32 (Fc gamma RII

Question 9

Expressed on: B cells

Function: receptor for C3b (complement)

Answer 9

CD35 (CR1)

Question 10

Expressed on: B cells

Function: signal transduction

Answer 10

CD40

Question 11

Expressed on: CD4+ T cells, CD8+ T cells, B cells, and NK cells
Function: signal transduction

Answer 11

CD45

Question 12

Expressed on: NK cells

Function: adhesion

Answer 12

CD56