Hypersensitivity Flashcards
1
Q
What is allergy mediated by?
A
IgE
It is an immediate reaction
2
Q
What type of T cells are hypersensitive in allergy?
A
TH cells
3
Q
What is a type II hypersensitivity reaction involved in?
A
Blood type
4
Q
Mast cells are primed with what immunoglobulin class?
A
IgE
5
Q
What compound is responsible for inflammation in atopy?
A
Histamine
6
Q
Which if these cells is predominantly found in type I hypersensitivity alone?
A
Eosinophils
7
Q
What form of hypersensitivity involves NK cells?
A
Type 2
8
Q
Which ligand bond is involved in the APC-Tc binding in a type 3 hypersensitivity?
A
CD40
9
Q
What compound is responsible for macrophage migration in Type IV hypersensitivity?
A
Interferon-Y (gamma)
10
Q
What T-Cell type contributes to type IV hypersensitivity?
A
TH1
