HYPERSENSITIVITY Flashcards
It is an exaggerated response to an innocuous antigen that results in changes that are deterious to the host
Hypersensitivity
It is also known as Immediate hypersensitivity
Type 1 hypersensitivity
What is the timeframe of symptom occurrence in Type 1 hypersensitivity?
Minutes to hours after exposure
Most common reaction of Type 1 hypersensitivity
Rhinitis
It is another term for hives
Wheal and Flare
What type of Ig is most commonly the mediator for sudden allergic response, or immediate hypersensitivity
IgE
What are the vasoactive mediators released from mast cells
Histamine
ECF-A
Neutrophil Chemotactic Factor
Tryptase
What are the newly synthesized mediators
Prostaglandins-enhances histamine effects
Leukotrienes- resembles effects of histamine but 100x more potent
It is an inherited tendency to respond to naturally occurring inhaled and ingested allergens with continued production of IgE
Atopy