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MTAP 1 > Hypersensitivity > Flashcards

Hypersensitivity Flashcards

1
Q

allergies

A

type 1

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2
Q

atopy

A

type 1

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3
Q

passive cutaneous anaphylaxis

A

type 1

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4
Q

hay fever (Seasonal allergic rhinitis)

A

type 1

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5
Q

allergic asthma

A

type 1

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6
Q

hives (urticaria)

A

type 1

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7
Q

latex sensitivity

A

type 1
type 4

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8
Q

wheal and flare rxn

A

type 1

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9
Q

eczema

A

type 1

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10
Q

dermatitis or local skin inflammation

A

type 1

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11
Q

drug anaphylaxis

A

type 1

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12
Q

rhinitis

A

type 1

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13
Q

angioedema

A

type 1

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14
Q

penicillin-induced rxn

A

type 1

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15
Q

food allergies

A

type 1

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16
Q

reaction to bee venom/sting

A

type 1

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17
Q

atopic dermatitis

A

type 1

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18
Q

transfusion rxn

A

type 2

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19
Q

drug induced AIHA
idiopathic AIHA
WAIHA

A

type 2

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20
Q

HDN

A

type 2

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21
Q

hyperacute graft rejection

A

type 2

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22
Q

goodpasture syndrome

A

type 2

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23
Q

Myasthenia gravis

A

type 2

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24
Q

Graves dse

A

type 2

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25
Q

type 2 DM (insulin independent)

A

type 2

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26
Q

ADCC

A

type 2

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27
Q

classical pathway of complement activation

A

type 2

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28
Q

cell surface coating by Ab

A

type 2

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29
Q

kernicterus (>20 mg/dL bilirubin)

A

type 2

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30
Q

erythroblastosis fetalis (severe HDN)

A

type 2

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31
Q

PCH

A

type 2

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32
Q

cold agglutinins

A

type 2

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33
Q

acrocyanosis

A

type 2

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34
Q

CCAD/CHD

A

type 2

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35
Q

Hashimoto’s

A

type 2 (pwede rin ata type 4???)

36
Q

SLE

37
Q

RA

38
Q

post strep glomerulonephritis

39
Q

vasculitis

40
Q

serum sickness

A

type 3
generalized

41
Q

arthus rxn

A

type 3
localized

42
Q

LE

43
Q

drug rxn

A

type 1 (penicillin)
type 2
type 3

44
Q

granulomas

45
Q

M. tuberculosis (TB)

46
Q

M. leprae (Leprosy)

47
Q

P. carinii

48
Q

Leishmania spp

49
Q

HSV

50
Q

poison oak/ivy

51
Q

nickel salts (metal)

52
Q

hair dye/cosmetic components

53
Q

contact dermatitis

54
Q

hypersensitivity pneumonitis

55
Q

tuberculin

56
Q

farmer’s lung
bird breeder’s lung dse
humidifier/AC lung dse

57
Q

type 1 DM

58
Q

acute/chronic graft rejection

59
Q

IMMUNE MEDIATOR: TYPE 1

60
Q

IMMUNE MEDIATOR: TYPE 2

A

IgG or IgM

61
Q

IMMUNE MEDIATOR: TYPE 3

A

IgG or IgM

62
Q

IMMUNE MEDIATOR: TYPE 4

63
Q

SYNONYM: TYPE 1

A

Anaphylactic

64
Q

SYNONYM: TYPE 2

A

Ab-mediated cytotoxic

65
Q

SYNONYM: TYPE 3

A

Immune Complex-mediated

66
Q

SYNONYM: TYPE 4

A

Cell-mediated or Delayed

67
Q

TIMING: Type 1, 2, 3

68
Q

TIMING: Type 4

69
Q
  1. mediated by antibodies
  2. mediated by sensitized T cells
A
  1. immediate hypersensitivity
  2. delayed
70
Q

ANTIGEN: Type 1

A

heterologous

71
Q

ANTIGEN: Type 2

A

cell surface
autologous
heterologous

72
Q

ANTIGEN: Type 3

A

soluble
autologous
heterologous

73
Q

ANTIGEN: Type 4

A

autologous
heterologous

74
Q

complement involvement: Type 1

75
Q

complement involvement: Type 2

76
Q

complement involvement: Type 3

77
Q

complement involvement: Type 4

78
Q

IMMUNE MECHANISM:

Mediator release from IgE-sensitized mast cells and basophils

79
Q

IMMUNE MECHANISM:

Cell destruction due to Ab and complement, opsonization, or ADCC

Cell function INHIBITED by Ab binding

Cell function STIMULATED by Ab binding

80
Q

IMMUNE MECHANISM:

Ag-Ab complex activates complement proteins
Neutrophils are recruited and release lysosomal enzymes that cause tissue damage

81
Q

IMMUNE MECHANISM:

Ag-sensitized Th1 cells release cytokines that recruit macrophage and induce inflammation or activate cytotoxic T cells to cause direct cell damage.

82
Q

Ab in type 4

A

NONE (difference from the 3 types)

83
Q

EFFECTOR CELLS: Type 1

A

Basophil
Mast cells

84
Q

EFFECTOR CELLS: Type 2

A

PMN
NK
MICROORG

85
Q

EFFECTOR CELLS: Type 3

A

PMN
MICROORG

86
Q

EFFECTOR CELLS: Type 4

MTAP 1 (13 decks)

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