Hypersensitivity

Question 1

what is the exaggerated, inappropriate adaptive immune response?

Answer 1

hypersensitivity

Question 2

what contact with the antigen does hypersensitivity manifest on?

Answer 2

the second

Question 3

how is hypersensitivity classified?

Answer 3

type I, II, III, IV

Question 4

What are types I, II and III mediated by?

Answer 4

antibodies

Question 5

what is type IV mediated by?

Answer 5

T cells and macrophages

Question 6

what is type I hypersensitivity?

Answer 6

immediate - allergy

Question 7

what immunoglobulin is responsible for type I?

Answer 7

IgE response to allergens

Question 8

what is a severe type I reaction ?

Answer 8

anaphylaxis

Question 9

when does type II hypersensitivity occur?

Answer 9

12-18 hours after exposure

Question 10

what immunoglobulins are responsible for type II hypersensitivity?

Answer 10

IgG/ IgM

Question 11

what are examples of type II reactions?/

Answer 11

blood transfusion incompatibility
haemolytic disease of newborn

Question 12

when does type III hypersensitivity occur?

Answer 12

18-24 hours after exposure

Question 13

what are examples of type III hypersensitivity?

Answer 13

extrinsic allergic alveolitis

Question 14

when does type IV occur?

Answer 14

48-72 hours post exposure

Question 15

what are the 3 types of type IV hypersensitivity?

Answer 15

contact
tuberculin
granulomatous

Question 16

where in the dental setting is type IV hypersensitivity seen?

Answer 16

amalgam
gold
mercury
resin-based materials