Hyperlipidema MoA Flashcards
1
Q
statin
A
inhibit HGM-CoA reductase
-decrease cholesterol biosynthesis
-increase LDL receptors on liver surface
2
Q
bile acid sequestrants
A
binds to bile acid to prevent reabsorption
-cholesterol lost in feces
-liver makes more LDL receptors
3
Q
niacin
A
increases HDL and decreases VLDL in large doses
4
Q
fibric acid meds
A
activate liproprotein lipase
-increase elimation of triglyceride-rice particles from plasma
5
Q
cholesterol absorption inhibitor
A
blocks cholesterol absorption in SI by 50%
