HF MoA Flashcards

1
Q

nesiritide

A

structurally identical to BNP (hormone secreted by heart)

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2
Q

beta-adrenergic antagonists

A

block high levels of catecholamine in HF pts
-slows cardiac remodeling

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3
Q

digoxin

A

inhibits Na-K-ATPase
-sodium accumulates in myocytes
-calcium released from intracellular storage
-increased forceful contraction

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4
Q

dobutamide

A

increased contractility w/o increasing HR and BP

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