Humoral immune response 2 Flashcards
What kind of immunoglobulins do naive B cells express?
IgM, IgD
repeated exposure to the same antigen causes what kind of antibody response?
affinity maturation (antibodies will be produced with increasing affinity for that antigen)
Mature B cells travel to the lymph node via the ____ and leave via the _____.
bloodstream, efferent lymph
How do B cells and Th cells enter the lymph node?
specialized venules called HEVs
What are dividing B cells called? Resting B cells?
centroblasts
centrocytes
After the initial interaction between antigen-activated B cells and Th cells, The B cells begin to divide, migrate to the ________, and differentiate into IgM secreting plasma cells.
medullary cords