Humoral immune response 1 Flashcards
What is an example of a passive artificial immune response?
immunoglobulins
What is an example of a passive natural immune response?
colostrum
What is an example of a active natural immune response?
disease
What is an example of a active artificial immune response?
vaccination
B cell receptors and antibodies belong to what superfamily of proteins?
immunoglobulins
What are hyper variable regions on the B cell receptor known as?
complementary determining regions (CDRs)
What are constant regions on the B cell receptor known as?
framework regions
What is B lymphocyte co-stimulation used for?
B cell activation
memory cell development
immunoglobulin class switching
Are B cells able to act as antigen presenting cells?
yes, during a secondary immune response
B cells in the germinal center undergo what?
somatic mutation after coming into contact with antigens presented by dendritic cells
What is IgG used for?
inflammation
activation of the classical complement pathway
agglutination
What is IgM used for?
primary immune response
virus neutralization
agglutination
activation of lectin complement pathway
What is IgA used for?
No complement activation
found in the GI, respiratory, urinary tracts, skin, mammary tissue
found in external secretions
What is IgE used for?
Inflammation
parasite immunity
shortest half life
attaches to mast cells and basophils
What is IgD used for?
attached to B cells
mediates link between innate and adaptive immune response
not found in cats, chickens, and rabbits
