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HRM > HRM W2 Insulin and other hypoglycemics > Flashcards

HRM W2 Insulin and other hypoglycemics Flashcards

1
Q

Metformin

A

Biguanide

impairs gluconeogenesis

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2
Q

Glimeperide and Glipizide

A

Sulfonylureas

bind SUR (receptor sub-unit) of K+ channel

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3
Q

Exanitide

A

GLP-1 Incretin analog

promote insulin secretion to GLP receptor/AC

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4
Q

Stigagliptin

A

DPP IV inhibitor

lengthen the t1/2 of incretins

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5
Q

Repaglinide and Nataglinide

A

Meglitinides/Glinides

bind to SUR1 of K+ channel

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6
Q

Acarbose and Miglitol

A

Alpha glucosidase inhibitor

impair GI absorption

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7
Q

Pramlinitide

A

Amylin analog

Inhibits glucagon secretion, slows gastric emptying, prootes satiety

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8
Q

Rosaglitazone and Piaglitazone

A

Thiazolidinediones: PPARg agonists

bind with RXR = Transcription factors. Promote glucose utilization/ transport into skeletal muscle

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HRM (8 decks)

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