HRM W1 Adrenal Function Tests and Pharmacology Flashcards

1
Q

Tetracosactide

A

short and long ACTH stimulation test

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2
Q

Parireotide

A

SS analog - suppresses ACTH

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3
Q

Gabergoline

A

D2 analog - suppresses ACTH

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4
Q

Mifepristone (RU 486)

A

glucocoriticoid receptor antagonist

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5
Q

Ketoconazole

A

nonselective inhibitor of steroidogenesis (inhibits side chain cleavage of CYP 11A1)

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6
Q

Aminoglutethimide

A

inhibits side chain cleavage enzyme CYP11A1

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7
Q

Etomidate

A

inhibits II beta hydroxylase CYP11B1

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8
Q

Metyrapone

A

inhibits II beta hydroxylase CYP11B1

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