How do cells die

Question 1

Hypoxia driven cell death

Answer 1

Decrease in O2 - decrease in ATP production from 36 (Oxidative Phosphorylation) to 2 (Glycolysis).

Na / K pump stop working and cellular Na increases - Water follows

Cell Lyses - ribosomes detach, cellular Ca increases

lysosomes release mediators which trigger Apoptosos

Cell wall breaks and mediators are released to other cells