Asthma

Question 1

Define Asthma

Answer 1

Breathing difficulties associated with exposure to an allergen or physical factor that leads to Inflammation, mucous secretions and Bronchospasm

Question 2

Fast onset asthma:

Cause
-examples

Mediator release =?
This leads to - 4

Answer 2

Environmental exposure (allergy)

• dust
• pollen
• dairy

IgE release causes Inflammation - leads to 
swelling and permeability (cytokines)
Increased mucous and
Tissue aggregation (neutrophils)
Bronchospasm (eosinophils)

Question 3

Slow onset Asthma

Caused by -3

Triggers release of?
Causes

Answer 3

Stress
Exercise
Cold

Eosinophils
Trigger Neutrophil recruitment (fast onset) neutrophils trigger mucous and aggregate tissue.
Bronchospasm

Question 4

Slow and fast onset asthma lead to?

Lung presentation

Leads to - 2

Answer 4

Increased RR and hyperinflation with a longer expiration phase.

Obstructive Shock
Hypoxia