How Anesthesia Works Flashcards
0
Q
Brain and spinal cord
A
Macroscopic
Decerebration does not alter requirements
1
Q
CNS
A
Macroscopic
Transmission disrupted throughout CNS
2
Q
Axon vs synapse
A
Atonal disruption needs higher concentration than synaptic disruption
Microscopic
3
Q
Excitatory vs inhibitory
A
Blockage and enhancement of excitatory transmission occurs
Microscopic
4
Q
Pre vs post synaptic
A
Intracellular Ca alters pre and other ions alter post
Microscopic
5
Q
Membrane
A
Meyer-Overton rule states the potency of an anesthetic is proportional to its lipid solubility;Lipophilic site of action
Molecule
6
Q
Lipid and protein
A
Both involved
