Host-microbe interactions Flashcards
the body is
not a uniform envrionment and has its own factors
lysozyme
sterlie in the blood stream
normal microbiota
dont cause disease under normal conditions
a lower virulence is
more likely to cause disease
infections
are caused by pathogens
parasites
live on the host
strict pathogens
only some can affect the host
opportunistic pathogens
can take advantage of a weakened immune systems
a host/ mircobe relationship depends on
host condition and pathogenicity
what are the 4 lochs prostulates
- the pathogen must be everywhere
- must be isolated and grow in pure culture
- can cause disease when put into something else
- shown to the original organism
what is the skin environment like
low in Aw and nutrition, dry has epidermis, dermis and sebaceous tissue
what are the 3 types of glands?
eccrine= finger tips
apocrine= underarms
sebaceous - hair follicles
stap epidermis on skin
it causes acne bc it makes oil and then acidifies it younger kids (-)
environment of oral cavity
saliva is the nutrition source
what are the 5 steps for oral activity
- thin film makes saliva glycoproteins
- colonization by spices of strep
- formation of plaque as biofilm thickens
4 growth of other microbes - too much plaque then dental
facultative
form in the GI tract so the deeper layers of the biofilm and grow
environment of the GI tract
stomach (2-4) small intestine (4-6) site of primary fluid absorption large intestine/ colon -7 -- no O and highest microbes
Environmental of respiratory tract
upper: has epiglottis, oral, throat
lower: lungs, sterile and cilial elevator
DPT (dipheria) causes
-> tetanus and Corynebacterium
environment of Urogenial tract
vag weak acidic
bladder is sterile
urethra is facultative and (-)
age is big factor
