Hopi Hoekstra Flashcards
video analyzes what
how changes in genes actually produce variation in phenotype on which NS acts
Darwin was wrong about what
the mechanism of evolutionary change of how organisms adapt to their environment
he knew traits were inherited but didn’t know how
Darwin’s last publication
- “on the dispersal of freshwater bivalves”
- report on finding freshwater beetle with a clam stuck to it, theory: was how cockles (clams) travel from lake to lake and why they were so similar in appearance
- Walter crick (Jim Watsons (dna guy) grandpa) sent Darwin a beetle and clam
DNA coding is evidence of Darwins great theory , 3 main ideas
a) 3 billion year existence
b) shared evolutionary history of all living organisms
c) the mechanistic basis for evolutionary change
HOW IS VARIATION GENERATED? = DNA
are adaptive alleles/mutations recessive or dominant
- JBS Haldane argued that they were dominant because theyre visible to selection and can spread quicker
REASONING:
*adaptive alleles tend to be dominant
= when they first appear they are visible to selection and can quickly spread where recessive mutations have to build up enough number in a population to be contained in the same individual
how is diversity generated and maintained
- the answer is the genetic code (discovered by Watson and crick)
- ## changes in gene produce variation in phenotypes on which NS can act
How many + what are the effect sizes of genes that contribute to adaptive phenotypes
= small changes/mutations
= large changes/mutations
adaptation flowchart
genotype —- phenotype
(via genetics, development)
phenotype= behaviour, morphology, physiology
phenotype — environment (natural selection)
SECOND VERSION
genotype—behaviour
(via genetics and neurobiology)
behaviour—-environment (natural selection)
deer mice
- found in almost all habitat types
- most abundant mammal in NA
- lots of opportunities for local adaptation
- can be used like lab mice for ctrlled experiments
- we have lots of history on their ecology and we can describe their change in behaviour, morphology, and physiology [i.e. burrowing behaviour]
= genetic + genomic tools can be used to try to make connections between phenotype and genotype