Homework 7 Flashcards

1
Q

Which of the following statements about macrophages is FALSE?

A

Typically reside in the lymphoid tissue.

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2
Q

what is true about macrophages

A

Antigen presenting cells that aid in the adaptive immune response, Phagocytes involved in the innate immune response, long lived

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3
Q

Which of the following statements about MHC class II molecules is true?

A

They present extracellular antigens.

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4
Q

what is false about MHC II molecules

A

They are used to present antigen to cytotoxic T-cells, They are found on all nucleated cells, They are used to present antigen to CD8 T-cells

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5
Q

An immune deficiency causes a severe reduction in the amount of MHC-II expressed on the surface of professional antigen presenting cells. Which immune processes will be LEAST impacted by this deficiency?

A

Cytotoxic T-cell activation

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6
Q

An immune deficiency causes a severe reduction in the amount of MHC-II expressed on the surface of professional antigen presenting cells. Which immune processes will be impacted by this deficiency?

A

B cell activation, antibody production, Fc-receptor phagocytosis by macrophages

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7
Q

Opsonization is a process whereby innate and adaptive immunity work together to…

A

phagocytose an invader.

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8
Q

Bacterial pathogens use specialized secretion systems to inject host cells with… while … are secreted to the extracellular space

A

effectors, toxins

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9
Q

All of the following are true of toxins EXCEPT. Multiple answers may be selected.

A

Only target host proecceses inside the cell, They only target host processes outside the cell, Are secreted through specialized secretion machince into host cells

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10
Q

what is true about toxins

A

They can be used to acquire nutrients, They can disrupt host cells processes outside or inside of the cell

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11
Q

The Yersina pestis T3SS injects effectors into cells expressing the… receptor to disrupt phagocytosis, which will prevent the development of… that might aid in clearing the infection.

A

fMET, humoral immunity

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12
Q

what do all viruses contain

A

a capsid and a genome

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13
Q

Enveloped viruses are most typically associated with … infections and are typically … stable to survival outside of the host

A

latent, less

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14
Q

what does not contribute to the inability to cure HIV

A

a segmented genome

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15
Q

what features of influenza A contribute to its capacity to cause global pandemics

A

segmented genome, broad host range

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16
Q

what do retrovirsuses do

A

make up a significant part of the human genome

17
Q

what is antigenic shift responsible for

A

generations of new strains of influenza

18
Q

what is antigenic drift responsible for

A

seasonal influenza epidemics

19
Q

what is influenza

A

an RNA dependent RNA polymerase

20
Q

what is reverse transcriptase used by

A

restroviruses to convert RNA to DNA