Homestatic Mechanisms & Kidneys (b1 & B10) Flashcards
Definition of homeostasis
Is the ability or tendency to maintain internal stability in an organism to compensate for environmental changes.
Keeping the same state such as sugar, water and Ph levels
Internal environment
Stimula
Sensor
Control
Effector
Negative feedback
Occurs when an important variable, such as the Ph blood tissue fluid, deviated from the acceptable range or limit, and triggers responses that return the variable to be within the acceptable normal range.
It is the feedback that creates a reaction to return the internal environment to be balanced, happy and healthy
Brain and nervous system control
The brain and nervous system play a vital role in controlling homeostatic mechanisms and helps humans think ahead of possible variables moving outside the normal range, advance thinking. This is feedfoward rather than getting to the feedback situation.
Thermoregatory homeostatic process
Body temp varies only slightly.
The skin plays a very important role in maintaining core temp. The hypothalamus is the processing centre in the brain that controls body temp. It does this by triggering changes to effectors, such as the sweat glands and muscles controlling body hair.
The skins (largest body organ)
- protect the underlying tissues against friction damage
- waterproof body
- protect deeper structures from microorganisms
- protect against UV radiation
- thermoregulation process
- relay sensory nerve messages
- synthesis vitamin D
Hyperthermia
A body temp ABOVE 37 degrees
Hypothermia
Body temp BELOW 37 degrees
glucose homeostasis
Glucose is a sugar needed by cells for respiration. It is important that the concentration of glucose in the blood is maintained at a constant level
Insulin basics
Insulin and gluocogen are hormones secreted by islet cells within the pancreas. They are both secreted in response to blood sugar levels, but in opposite fashion! Insulin is normally secreted by the beta cells (a type of islet cells) of the pancreas
Insulin, glucogen, and other hormone levels rise and fall to keep blood sugar in s normal range…
When blood sugar drops too low, the level of insulin declines and other cells in the pancreas release glucogen, which causes the liver to turn stored glycogen back into glucose and release it in to the blood.
ISLET CELLS
Cells in pancreas that produce insulin
GLUCOSE
Provides the energy in the blood and it must be at correct level
GLUCAGEN
Hormone released by pancreas which converts into glucogen to increase blood sugar levels
INSULIN
The hormone secreted by begs cells in pancreas that converts glucose into glucogen
LIVER
The liver sorted glucogen
MUSCLE CELLS
The muscle cells store glycogen
DIABETES
Diabetes is where the blood glucose levels remain too high. By injecting insulin which causes the liver to convert glucose into glycogen which reduce the glucose level.
Type 1 - lack of insulin controlled by monitoring diet and injecfing insulin.
Type 2 - body becoming resistant to insulin
THE KIDNEYS
The kidney is surrounded by a renal capsule and the cortex.
Urine formed in the correct passes through the minor then major calyx
RENAL PELVIS
Urine from the calyx then passes into the renal pelvis and continues put down the ureter.
URETER
Near the belly button
URETHRA
Where you urinate
BLADDER
Many muscles control the bladder but the main one is the sphincter which releases and stop the stream of urine
What is the NEPHRON?
Blood travels in through the renal artery. Waste products are FILTERED out and NUTRIENTS absorbed.
The BALANCE of water in the body is regulated. The RENAL VEIN takes the blood AWAY. WASTE PRODUCTS in urine move DOEN the BLADDER.
The role of the KIDNEY and the RENAL SYSTEM
Keep the CONCENTRATIONS. Of the various IONS and other important substances CONSTANT
Keep the volume of WATER in your body constant
The the ACID/BASE CONCENTRATION of your blood CONSTANT
Help regulate BLOOD PRESSURE
NEPHRON
The filtering unit of the kidney which performs the job of filtering and fluid balance jobs.
Each KIDNEY is made up of MANY NEPHRONS
THE GLOMERULUS
At the beginning of the nephron is the GLOMERULUS a network of capillaries that performs the first step of filtering blood using diffusion
Labelling a nephron
BOWMAN CAPSULE PROXIMAL TUBULE DISTAL TUBULE LOOP OF HENLE COLLECTING DUCT
BOWMANS CAPSULE
Fluids from blood in the glomerulus are collecting in the bowmans capsule (the glomerular filtrate) and further processed along the nephron to form urine this process is known as ULTRA FILTRATION
ULTRA FILTRATION
The Hugh pressure forces small molecules such as water, glucose, amino acids,. Sodium chloride and urea through the filter, from the blood in the GLOMERULAR CAPSULE across the basement membrane of the BOWMANS CAPSULE into the NEPHRON
PROXIMAL TUBULE
The filtrate is passed through the PROXIMAL TUBULE, LOOP OF HENLE, and DISTAL TUBULE, where water and nutrients are reabsorbed, producing HYPERSMOTIC URINE
REABSORPTION
Water gets reabsorbed passively by osmosis
END RESULTS
Urine from the nephrons flow into a collecting duct, leading to the renal pelvis, which is drained by the ureter.