Homeostasis & Control Systems - Lecture 3 Flashcards
Homeostasis
Maintenance of a constant internal environment
Negative feedback control
○ Maintain a controlled variable at its set point
○ Change in variable -> sensor -> integrating centre -> effector
Diurnal body temperature changes
Body temperature fluctuates throughout the day with the lowest during sleep
Positive feedback
○ Not as common
○ Initial stimulus causes a response which reinforces itself
○ Examples:
- Ovulation
- Blood clotting
- action potential in nerves
Nervous vs Endocrine
○ Rapid, short term effects
○ long-term effects
Sympathetic Nerves
○ Active in stressful situations
○ Origin: thoracic & lumbar
○ Short preganglionic
○ Long postganglionic
○ Ganglionic transmitter: Acetylcholine -> N2 receptor
○ Neuroeffector transmitter: norephinephrine -> α or β
Parasympathetic nerves
○ Active in vegetative situations
○ Origin: cranial & sacral
○ Long preganglionic
○ Short postganglionic
○ Ganglionic transmitter: acetylcholine -> N2 receptor
○ Neuroeffector transmitter: acetylcholine > muscaranic receptor
Cortisol hormonal control
○ Negative feedback
○ CRH → ACTH → Cortisol
Milk production control
○ Positive feedback
○ Suckling → Oxytocin → Milk