Homeostasis- BP Flashcards

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1
Q

Job of the hormonal system?

A
  • coordinates the response to certain stimuli
  • involves chemical messengers released by endocrine glands into the blood, travels to target cells causing changes
  • protein hormones bind to complementary receptors on target cells
  • activates enzymes that convert ATP into Cyclic AMP in the cell
  • the Cyclic AMP then makes changes in the cell (=2nd messenger system) e.g. insulin
  • lipid hormones enter cells by simple diffusion and cause direct changes e.g. oestrogen
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2
Q

control of blood glucose levels?

A

 if high = should be in cells for respiration, also lowers blood water potential
 if low = not enough to supply cells of the brain, also increases blood water potential
 controlled by the Pancreas
 contains the Islets of Langerhans
 made of alpha and beta cells
 alpha cells produce glucagon
 beta cells produce insulin

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3
Q

What happens with High Blood Glucose Levels?

A

 occurs after a meal
 insulin is released
 most cells in the body have complementary receptors (particularly muscle, liver, brain cells)
 causes increase in glucose channels and carriers
 glucose taken up and used in respiration
 in muscle and liver cells, glucose also converted into glycogen for storage (glycogenesis)
 in liver cells, glucose also converted into fat

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4
Q

What happens with Low Blood Glucose Levels?

A

 occurs after starvation or exercise
 glucagon is released
 only liver cells have complementary receptors
 converts glycogen into glucose (glycogenolysis)
 converts fats and amino acids into glucose (gluconeogenesis)
 glucose is released into blood

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5
Q

Diabetes?

A

 person loses control of blood glucose levels
 normally high (hyperglycaemia)
 2 types: type 1 and type 2
 type 1 starts at young age, person does not make insulin, beta cells damaged by an autoimmune disorder (treatment = insulin injections)
 type 2 starts at middle age, person makes insulin but cells are less sensitive, caused by obesity and diet high in simple sugars (treatment = diet and exercise, drugs, insulin injection)

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6
Q

What is Homeostasis?

A

 maintenance of a constant internal environment (the blood and tissue fluid) in animals
 control body temperature, blood pH, blood glucose levels, blood water levels, blood salt levels, blood pressure

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7
Q

Homeostasis and Negative Feedback?

A
  • the response to the change is to oppose the change to bring levels back to normal
  • (e.g. body temperature increases – response is to bring it down to normal, blood glucose levels decrease – response is to increase it back to normal)
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8
Q

What is Positive Feedback?

A

the response to the change is to continue the change (e.g. Na+ ions entering a neurone stimulating more to enter in depolarisation)

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9
Q

Why do organisms need to maintain a constant body temperature?

A

for enzyme activity

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10
Q

What are Endotherms and Ectotherms

A

 endotherms = animals that maintain a strict constant internal body temperature irrespective of external environmental temperature (e.g. mammals)
 ectotherms = animal’s internal body temperature maintained more generally and varies with changes in external environmental temperature (e.g. reptiles)

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11
Q

Benefit of being an Endotherm?

A

can maintain activity over a range of settings e.g. early morning or winter

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12
Q

Benefit of being an Endotherm?

A

can maintain activity over a range of settings e.g. early morning or winter

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13
Q

Benefit of being an Ectotherm?

A

 require less food/energy

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14
Q

How is internal body temperature controlled?

A

 anatomical, behavioural, physiological changes
 ecotherms mainly rely on behavioural changes
 endotherms mainly rely on physiological changes

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15
Q

Anatomical adaptations in organisms in warm areas?

A

 small body size = large surface area to volume ratio (lose heat)
 less fur
 less fat
 large extremities e.g. ears/hand/feet (lose heat)

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16
Q

Anatomical adaptations in organisms in cold areas?

A

 large body size = small surface area to volume ratio
 more fur
 more fat
 small extremities

17
Q

Behavioural/Physiological changes in Ectotherms?

A

 warming up = expose to sun, press on warm surface, darker skin colouration to absorb heat, more respiration in liver, less breathing
 cooling down = shade from sun, press on cold surface, lighter skin colouration, less respiration in liver, more breathing

18
Q

Control of Body Temperature in Endotherms?

A

 controlled by Hypothalamus in the brain
 receives nerve impulse from peripheral thermoreceptors in the skin and central thermoreceptors in the hypothalamus
 peripheral thermoreceptors monitor changes in external environmental temperature
 central thermoreceptors monitor changes in core body temperature (blood supplying major organs)

19
Q

How an Endotherm warms itself up?

A
  • reduce blood flow to the skin surface = vasoconstriction, smooth muscle in arterioles to the skin contract, lumen narrows, less blood to skin surface, less heat lost from blood by radiation
  • hair on skin stands up = hair erector muscles contract, hairs stand up, traps in air particles, forms an insulating layer, reduces heat loss
  • shivering = involuntary contraction of muscles – friction in sliding filament mechanism generates heat and respiration generates heat
  • increase respiration in liver = generates heat
20
Q

How an Endotherm cools itself down?

A

 increase blood supply to skin surface = vasodilation, smooth muscle in arterioles to the skin relax, lumen widens, more blood to skin surface, more heat lost from blood by radiation
 sweating = evaporation of water particles from the skin surface using the heat in the blood

21
Q

symptoms of diabetes?

A

tiredness, increase urination, thirst

22
Q

diagnosis of diabetes?

A

high blood glucose levels on random testing & blood glucose levels remain high following a fasting blood glucose test (person fasts for a number of hours, then consumes a drink of glucose, should normally rise then decrease due to insulin)

23
Q

gluconeogenesis?

A

non-carbohydrate molecules into glucose

24
Q

glycogenesis?

A

glucose to glycogen