Homeostasis Flashcards
What is homeostasis?
The maintenance of a stable internal
environment in the body despite
fluctuations in internal and external
conditions.
Why is homeostasis important?
To ensure optimum conditions for enzymes
and cellular processes in the body
State three conditions within the body that must be
controlled by homeostasis
● Temperature
● Blood glucose concentration
● Water levels
What is thermoregulation?
The maintenance of core body
temperature
Why must body temperature be controlled?
Enzymes work best at their optimum
temperature. Deviations from this optimum
temperature decrease the rate of
enzyme-controlled reactions.
What is the optimum temperature for enzymes in the
human body?
37°C
What does the maintenance of an ideal body
temperature depend on?
A negative feedback system involving:
● Receptors
● Hypothalamus
● Effectors e.g. sweat glands, hair erector muscles
Where are temperature-sensitive receptors located?
● Skin - epidermis (outer layer) and dermis
(below epidermis)
● Hypothalamus
What is the function of receptors in the skin and in
the hypothalamus?
They detect changes in blood
temperature and send information to the
hypothalamus.
What is the function of the hypothalamus?
It coordinates information from the
receptors and sends instructions to the
effectors.
What is the function of the effectors in thermoregulation?
They produce a response to counteract
the change in blood temperature and
return it to the set point.
Outline the responses of the body to an increase in
temperature above 37°C (3)
● Vasodilation
● Sweating
● Erector muscles relax, hairs lie flat
What structure produces sweat?
Sweat glands found in the dermis
How is sweat released from the skin?
Pores in the epidermis release sweat onto
the skin’s surface which then evaporates.
How does sweating help to reduce body
temperature?
Heat energy is used to evaporate sweat.
Increased heat transfer from the skin to the
environment decreases body temperature.
What is vasodilation?
● Dilation of blood vessels near the skin surface
● Blood flows closer to the skin surface
● Greater heat loss to the surroundings
Outline the responses of the body to a decrease in
temperature below 37°C
● Vasoconstriction
● Shivering
● Hair erector muscles contract
● Little sweat is produced
How does shivering help to increase body
temperature?
Involuntary contraction of muscles
generates heat energy from respiration
How does the contraction of hair erector muscles
help to increase body temperature?
Hairs stand on end creating pockets of
air between hairs and a layer of
insulation, which traps the warm air.
What is vasoconstriction?
● Constriction of blood vessels near skin surface
● Less blood flows close to the skin surface
● Less heat loss to the surroundings
Which organ is responsible for the maintenance of
blood glucose concentrations?
Pancreas
How are blood glucose concentrations controlled?
Controlled by the hormones insulin and
glucagon which are secreted by the
pancreas
Insulin and glucagon are antagonistic hormones.
What does this mean?
They have opposite effects which
counteract one another
Describe the role of insulin in the regulation of blood
sugar levels
● Causes liver and muscle cells to increase their
uptake of glucose from the blood
● Glucose is converted into glycogen, a storage
molecule
Describe the role of glucagon in the regulation of
blood sugar levels
● Causes the breakdown of glycogen to
glucose in the liver
● Glucose is released into the blood
What is the control of blood glucose concentration
an example of?
Negative Feedback
Describe what happens when blood glucose
concentrations become too high
● Blood glucose concentration increases above a set point
● Pancreas secretes insulin and stops producing glucagon
● Liver and muscle cells increase uptake of glucose
● Glucose is converted to glycogen and stored
● Some glucose may be stored as lipid in tissues
● Blood glucose concentration decreases, returning to normal levels
Describe what happens when blood glucose
concentrations become too low
● Blood glucose concentration decreases below a set point
● Pancreas secretes glucagon and stops producing insulin
● Liver cells convert glycogen into glucose which is released into blood
● Blood glucose concentration increases, returning to normal level
What is diabetes?
A condition where the homeostatic
control of blood glucose levels stops
working.
What is the cause of type 1 diabetes?
Pancreas does not produce any
insulin