Homeostasis Flashcards

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1
Q

What is homeostasis?

A

The maintenance of a stable internal
environment in the body despite
fluctuations in internal and external
conditions.

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2
Q

Why is homeostasis important?

A

To ensure optimum conditions for enzymes

and cellular processes in the body

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3
Q

State three conditions within the body that must be

controlled by homeostasis

A

● Temperature
● Blood glucose concentration
● Water levels

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4
Q

What is thermoregulation?

A

The maintenance of core body

temperature

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5
Q

Why must body temperature be controlled?

A

Enzymes work best at their optimum
temperature. Deviations from this optimum
temperature decrease the rate of
enzyme-controlled reactions.

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6
Q

What is the optimum temperature for enzymes in the

human body?

A

37°C

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7
Q

What does the maintenance of an ideal body

temperature depend on?

A

A negative feedback system involving:

● Receptors

● Hypothalamus

● Effectors e.g. sweat glands, hair erector muscles

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8
Q

Where are temperature-sensitive receptors located?

A

● Skin - epidermis (outer layer) and dermis
(below epidermis)

● Hypothalamus

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9
Q

What is the function of receptors in the skin and in

the hypothalamus?

A

They detect changes in blood
temperature and send information to the
hypothalamus.

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10
Q

What is the function of the hypothalamus?

A

It coordinates information from the
receptors and sends instructions to the
effectors.

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11
Q

What is the function of the effectors in thermoregulation?

A

They produce a response to counteract
the change in blood temperature and
return it to the set point.

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12
Q

Outline the responses of the body to an increase in

temperature above 37°C (3)

A

● Vasodilation

● Sweating

● Erector muscles relax, hairs lie flat

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13
Q

What structure produces sweat?

A

Sweat glands found in the dermis

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14
Q

How is sweat released from the skin?

A

Pores in the epidermis release sweat onto

the skin’s surface which then evaporates.

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15
Q

How does sweating help to reduce body

temperature?

A

Heat energy is used to evaporate sweat.
Increased heat transfer from the skin to the
environment decreases body temperature.

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16
Q

What is vasodilation?

A

● Dilation of blood vessels near the skin surface

● Blood flows closer to the skin surface

● Greater heat loss to the surroundings

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17
Q

Outline the responses of the body to a decrease in

temperature below 37°C

A

● Vasoconstriction

● Shivering

● Hair erector muscles contract

● Little sweat is produced

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18
Q

How does shivering help to increase body

temperature?

A

Involuntary contraction of muscles

generates heat energy from respiration

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19
Q

How does the contraction of hair erector muscles

help to increase body temperature?

A

Hairs stand on end creating pockets of
air between hairs and a layer of
insulation, which traps the warm air.

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20
Q

What is vasoconstriction?

A

● Constriction of blood vessels near skin surface

● Less blood flows close to the skin surface

● Less heat loss to the surroundings

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21
Q

Which organ is responsible for the maintenance of

blood glucose concentrations?

A

Pancreas

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22
Q

How are blood glucose concentrations controlled?

A

Controlled by the hormones insulin and
glucagon which are secreted by the
pancreas

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23
Q

Insulin and glucagon are antagonistic hormones.

What does this mean?

A

They have opposite effects which

counteract one another

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24
Q

Describe the role of insulin in the regulation of blood

sugar levels

A

● Causes liver and muscle cells to increase their
uptake of glucose from the blood

● Glucose is converted into glycogen, a storage
molecule

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25
Q

Describe the role of glucagon in the regulation of

blood sugar levels

A

● Causes the breakdown of glycogen to
glucose in the liver
● Glucose is released into the blood

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26
Q

What is the control of blood glucose concentration

an example of?

A

Negative Feedback

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27
Q

Describe what happens when blood glucose

concentrations become too high

A

● Blood glucose concentration increases above a set point

● Pancreas secretes insulin and stops producing glucagon

● Liver and muscle cells increase uptake of glucose

● Glucose is converted to glycogen and stored

● Some glucose may be stored as lipid in tissues

● Blood glucose concentration decreases, returning to normal levels

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28
Q

Describe what happens when blood glucose

concentrations become too low

A

● Blood glucose concentration decreases below a set point

● Pancreas secretes glucagon and stops producing insulin

● Liver cells convert glycogen into glucose which is released into blood

● Blood glucose concentration increases, returning to normal level

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29
Q

What is diabetes?

A

A condition where the homeostatic
control of blood glucose levels stops
working.

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30
Q

What is the cause of type 1 diabetes?

A

Pancreas does not produce any

insulin

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31
Q

How is type 1 diabetes treated? (3)

A

● Daily insulin injections at meal times

● Limiting intake of refined sugars

● Regular exercise

32
Q

What is the cause of type 2 diabetes?

A

Person develops insulin resistance or
doesn’t produce enough insulin (often
due to obesity)

33
Q

How is type 2 diabetes treated?

A

● Balanced diet
(eating fewer simple sugars and replacing them with more
complex carbohydrates)
● Exercise
● Medication or insulin injections (however, these are
less effective)

34
Q

How does exercise help to control diabetes?

A

Exercise increases respiration in muscle
cells. Excess glucose is removed from
the blood to produce energy in the form
of ATP.

35
Q

Why are type 2 diabetics advised to replace simple

carbohydrates with more complex carbohydrates?

A

● Simple carbohydrates are broken down quickly so
can raise blood glucose levels rapidly.

● Complex carbohydrates take longer to break
down so have a reduced effect on blood glucose
levels.

36
Q

What is the Body Mass Index (BMI)?

A

A value based on height and mass used to
categorise an individual as underweight, normal
weight, overweight or obese.

37
Q

How is BMI calculated?

A

BMI = kg/m^2

38
Q

What BMI values indicate obesity and an increased

risk of type 2 diabetes?

A

BMI value larger than 30

39
Q

How is an individual’s waist-to-hip ratio calculated?

A

waist-to-hip ratio = waist circumeference (cm)/ hip circumference (cm)

40
Q

What does a waist-to-hip ratio higher than 1.0 in

males or 0.85 in females indicate?

A

● Abdominal obesity

● Increased risk of developing type 2 diabetes

41
Q

What is osmoregulation?

A

The maintenance of constant water

levels in the body fluids of an organism

42
Q

Why is osmoregulation important?

A

Prevents cells bursting or shrinking when

water enters or leaves by osmosis

43
Q

Describe what happens to an animal cell if it is
placed into a solution with a higher water
concentration

A

● Higher concentration of water in surrounding solution

● Water molecules move down their water concentration
gradient into the cell by osmosis

● Pressure inside the cell increases, cell bursts (lysis)

44
Q

Describe what happens to an animal cell if it is
placed into a solution with a lower water
concentration

A

● Lower concentration of water in surrounding solution
● Water molecules move down their water concentration
gradient out of the cell by osmosis
● Pressure inside the cell decreases, cell shrinks (crenation)

45
Q

Describe what happens to an animal cell if it is
placed into a solution with an equal water
concentration

A

No net movement of water molecules

into or out of the cell

46
Q

Describe the function of the kidneys

A

● Removes toxic waste substances from the body

● Alters blood water levels

● Alters blood ion levels

47
Q

What is urine?

A

Waste product of the kidney that
contains urea, excess water and excess
ions

48
Q

How is urea produced?

A

In the liver, urea is produced from the

breakdown of excess amino acids.

49
Q

Identify the structures of
the urinary system
labelled in the diagram

A
A= kidney
B = renal vein
C = renal artery
D = ureter
E = urethra
F = bladder

https://www.physicsandmathstutor.com/pdf-pages/?pdf=https%3A%2F%2Fpmt.physicsandmathstutor.com%2Fdownload%2FBiology%2FGCSE%2FNotes%2FEdexcel%2F7-Animal-Coordination-Control-and-Homeostasis%2FFlashcards%2FFlashcards%2520-%2520Topic%25207%2520Homeostasis%2520-%2520Edexcel%2520Biology%2520GCSE.pdf

Page 98

50
Q

What is the function of the renal artery?

A

Supplies blood to the kidneys

51
Q

What is the function of the renal vein?

A

Drains blood from the kidneys

52
Q

What is the function of the ureter?

A

Takes urine to the bladder from the

kidneys

53
Q

What is the function of the urethra?

A

Releases urine from the bladder, out of

the body

54
Q

What is a nephron?

A

Functional unit of the kidney where
filtration and selective reabsorption takes
place

55
Q

Describe filtration in the kidneys

A

● Blood flows through the glomerulus under high
pressure
● Small molecules (e.g. urea, glucose), water and
ions are filtered out of the blood and into the
Bowman’s capsule of the nephron

56
Q

Why do large molecules (e.g. red blood cells,

proteins) remain in the blood?

A

They are too large to fit through the

pores in the capillary walls

57
Q

Which substances are selectively reabsorbed from

the nephron tubule?

A

● All sugars

● Some water

● Some ions

58
Q

What happens to the molecules not selectively

reabsorbed?

A

They travel down the kidney tubule as
urine and are transported to the bladder
via the ureter. Here they are stored and
eventually excreted.

59
Q

How is the concentration and volume of urine

controlled?

A

Controlled by the secretion of

anti-diuretic hormone (ADH)

60
Q

What producesADH?

A

Pituitary gland

61
Q

Describe how ADH affects the reabsorption of water

from the kidney tubules

A

ADH increases the permeability of the
collecting ducts, enabling more water to
be reabsorbed into the blood.

62
Q

What is required to maintain the ideal water content

of blood?

A

A negative feedback system involving:

● Receptors in the hypothalamus

● Hypothalamus

● Effector i.e. pituitary gland

63
Q

Describe the negative feedback loop which occurs

when low blood water concentration is detected

A

● Pituitary gland detects low blood water content.

● Pituitary gland increases ADH secretion.

● ADH increases collecting duct
permeability so more water is reabsorbed.

● Blood water content increases. More concentrated urine is produced.

●Blood water levels returns to normal

64
Q

Describe the negative feedback loop which occurs

when high blood water concentration is detected

A

● Pituitary gland detects high blood water levels

● Pituitary gland secretes less ADH.

● Collecting duct becomes less permeable so less water is reabsorbed.

● A large volume of dilute urine is produced.

● Blood water levels return to normal.

65
Q

How can kidney failure be treated?

A

● Kidney dialysis

● Kidney transplant

66
Q

What is kidney dialysis?

A

A machine artificially filters a patient’s

blood

67
Q

How does kidney dialysis work?

A

● Selectively permeable barrier or membrane separates patient’s blood from
dialysis fluid

● Materials are exchanged across the barrier e.g. urea, excess
ions and water move out of the blood and into the dialysis fluid through osmosis

● Large cells and proteins remain in the blood

68
Q

Describe the composition of dialysis fluid

A

● Same concentration of glucose and ions as in normal blood plasma
● No urea

69
Q

What does a kidney transplant involve?

A

Taking a kidney from a living donor or
someone recently deceased and
implanting it into the patient.

70
Q

What is the risk associated with kidney transplants?

A

Risk of the body rejecting the

transplanted kidney

71
Q

What precautions are taken to minimise the risk of

rejection?

A

● Tissue typing ensures that the transplanted
organ is ‘compatible’ with the recipient

● Immunosuppressant drugs help prevent the
immune system from rejecting the organ

72
Q

Ultrafiltration?

A

Water, glucose and Urea move into the Nephron at the Bowman’s capsule, out of the glomerulus under high pressures.

73
Q

Selective Reabsorption

A

Selective Reabsorption of glucose and some mineral ions by active transport in the first convoluted tubule.

74
Q

Reabsorption of water?

A

Reabsorption of water by osmosis, depending on how much the body needs. This happens in the loop of Henle and collecting duct.

75
Q

Urine formed

A

At the end of Nephron, the remaining fluid flows into the ureter. It contains excess water, urea and other substances.