Hodge Podge Flashcards
tram track
membranoproliferative glomerulonephritis
basketweave
Alport syndrome
wire loops
lupus nephritis
onion skin
hypertensive nephropathy or scleroderma
TTP, HUS
foot process effacement
MCD
spike and dome
membranous nephropathy
subepithelial humps
post infectious glomerulonephritis
soluble urokinase- type plasminogen activator receptor (suPAR)
FSGS
circulating permeability factor
apoL1
part of a complex that lyses parasites
mutations lead to resistance to Trypanosome brucei rhodesiense (African sleeping sickness): does not bind trypanosomes protein that blocks apoL1
arterionephrosclerosis, FSGS, HIV nephropathy
M-type PLA2
primary (idiopathic) membranous nephropathy
podocyte receptor
NEP
congenital membranous nephropathy
anti-streptolysin O
PSGN
throat infection
Ab against exotoxin B of S. progenies planted in GBM
anti-DNAse B
PSGN
skin infection
anti-hyaluronidase
PSGN
skin infection
C3 nephritic factor
MPGN type 2
stabilizes C3 convertase
factor H deficiency
MPGN
continued C3 activation
galactose deficient IgA1
IgA nephropathy
alpha 3 subunit of type IV collagen defect (COL4A3)
auto Ab: Goodpasture’s
or
AR Alport’s
alpha 5 collagen type IV (COL4A5)
X linked Alport’s
alpha 4 collagen type IV (COL4A4)
AR Alport’s
Hep. C
polyartertitis nodosa
type 1 membranoproliferative glomerulonephritis
cryoglobinemia
crescent
pauci-immune: vasculitis
lupus nephritis
Goodpasture
bad news bears
schistocytes
seen in hemolytic anemia
HUS, TTP
shigatoxin
HUS
S. pneumoniae
HUS
ADAMTS13
TTP
can’t cut von Willebrand factor
lupus
black females
malar rash, arthralgia
LOW C3, C4
anti-dsDNA
full house IF
lupus nephritis
polycystin-1/2
AD polycystic kidney disease
fibrocystin
AR polycystic kidney disease
ADPKD1/2
polycystic kidney disease
citrate
inhibitor for Ca stones
envelope crystal
Ca oxalate stones
diamond crystal
uric acid stones
coffin lid crystal
triple phosphate
magnesium ammonium phosphate
hexagon crystal
cystine stones
VHL
hereditary clear cell carcinoma
inactivated mutation or hypermethylation
normal: inhibits HIF that stimulates VEGF
translocation or deletions on chromosome 3
sporadic clear cell carcinoma
trisomy 7
papillary carcinoma
MET
papillary carcioma
mutated: activated
TK that hepatocyte growth factor binds
sicca syndrome
dry mouth and eyes due to inflammation of glands
LIGHT CHAIN disease
meltzer’s triad
cryoglobulinemia
purpura, arthralgia, weakness
kimmelstiel wilson nodules
ovoid or sphereical, hyaline, sometimes laminated deposits of mucopolysacchrides, lipids, and fibrillary proteins within mesangium in periphery of glomerular tuft
eventually squeeze capillaries shut
DIABETIC NEPHROPATHY
UTI cause
E. coli
Staph saprophyticus: sex. active women
UTI pos. leukocyte esterase
produced by monocytes, neutrophils, and eosinophils
bacterial
UTI pos. nitrite
gram negative
UTI pos. urease
Proteus or Klebsiella
UTI neg. urease
E. coli, Enterococcus