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SS- Renal > Hodge Podge > Flashcards

Hodge Podge Flashcards

1
Q

tram track

A

membranoproliferative glomerulonephritis

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2
Q

basketweave

A

Alport syndrome

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3
Q

wire loops

A

lupus nephritis

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4
Q

onion skin

A

hypertensive nephropathy or scleroderma

TTP, HUS

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5
Q

foot process effacement

A

MCD

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6
Q

spike and dome

A

membranous nephropathy

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7
Q

subepithelial humps

A

post infectious glomerulonephritis

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8
Q

soluble urokinase- type plasminogen activator receptor (suPAR)

A

FSGS

circulating permeability factor

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9
Q

apoL1

A

part of a complex that lyses parasites
mutations lead to resistance to Trypanosome brucei rhodesiense (African sleeping sickness): does not bind trypanosomes protein that blocks apoL1
arterionephrosclerosis, FSGS, HIV nephropathy

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10
Q

M-type PLA2

A

primary (idiopathic) membranous nephropathy

podocyte receptor

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11
Q

NEP

A

congenital membranous nephropathy

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12
Q

anti-streptolysin O

A

PSGN
throat infection
Ab against exotoxin B of S. progenies planted in GBM

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13
Q

anti-DNAse B

A

PSGN

skin infection

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14
Q

anti-hyaluronidase

A

PSGN

skin infection

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15
Q

C3 nephritic factor

A

MPGN type 2

stabilizes C3 convertase

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16
Q

factor H deficiency

A

MPGN

continued C3 activation

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17
Q

galactose deficient IgA1

A

IgA nephropathy

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18
Q

alpha 3 subunit of type IV collagen defect (COL4A3)

A

auto Ab: Goodpasture’s
or
AR Alport’s

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19
Q

alpha 5 collagen type IV (COL4A5)

A

X linked Alport’s

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20
Q

alpha 4 collagen type IV (COL4A4)

A

AR Alport’s

21
Q

Hep. C

A

polyartertitis nodosa
type 1 membranoproliferative glomerulonephritis
cryoglobinemia

22
Q

crescent

A

pauci-immune: vasculitis
lupus nephritis
Goodpasture
bad news bears

23
Q

schistocytes

A

seen in hemolytic anemia

HUS, TTP

24
Q

shigatoxin

A

HUS

25
Q

S. pneumoniae

A

HUS

26
Q

ADAMTS13

A

TTP

can’t cut von Willebrand factor

27
Q

lupus

A

black females
malar rash, arthralgia
LOW C3, C4
anti-dsDNA

28
Q

full house IF

A

lupus nephritis

29
Q

polycystin-1/2

A

AD polycystic kidney disease

30
Q

fibrocystin

A

AR polycystic kidney disease

31
Q

ADPKD1/2

A

polycystic kidney disease

32
Q

citrate

A

inhibitor for Ca stones

33
Q

envelope crystal

A

Ca oxalate stones

34
Q

diamond crystal

A

uric acid stones

35
Q

coffin lid crystal

A

triple phosphate

magnesium ammonium phosphate

36
Q

hexagon crystal

A

cystine stones

37
Q

VHL

A

hereditary clear cell carcinoma
inactivated mutation or hypermethylation
normal: inhibits HIF that stimulates VEGF

38
Q

translocation or deletions on chromosome 3

A

sporadic clear cell carcinoma

39
Q

trisomy 7

A

papillary carcinoma

40
Q

MET

A

papillary carcioma
mutated: activated
TK that hepatocyte growth factor binds

41
Q

sicca syndrome

A

dry mouth and eyes due to inflammation of glands

LIGHT CHAIN disease

42
Q

meltzer’s triad

A

cryoglobulinemia

purpura, arthralgia, weakness

43
Q

kimmelstiel wilson nodules

A

ovoid or sphereical, hyaline, sometimes laminated deposits of mucopolysacchrides, lipids, and fibrillary proteins within mesangium in periphery of glomerular tuft
eventually squeeze capillaries shut
DIABETIC NEPHROPATHY

44
Q

UTI cause

A

E. coli

Staph saprophyticus: sex. active women

45
Q

UTI pos. leukocyte esterase

A

produced by monocytes, neutrophils, and eosinophils

bacterial

46
Q

UTI pos. nitrite

A

gram negative

47
Q

UTI pos. urease

A

Proteus or Klebsiella

48
Q

UTI neg. urease

A

E. coli, Enterococcus

SS- Renal (11 decks)

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