HOCM Flashcards
1
Q
What is hypertrophic obstructive cardiomyopathy (HOCM)?
A
An autosomal dominant disorder of muscle tissue caused by defects in the genes encoding contractile proteins.
2
Q
What is the estimated prevalence of HOCM?
A
1 in 500.
3
Q
What are the management options for HOCM?
A
- Amiodarone
- Beta-blockers or verapamil for symptoms
- Cardioverter defibrillator
- Dual chamber pacemaker
- Endocarditis prophylaxis*
4
Q
What drugs should be avoided in HOCM?
A
- Nitrates
- ACE-inhibitors
- Inotropes
5
Q
True or False: HOCM is a recessive disorder.
A
False
6
Q
Fill in the blank: HOCM is caused by defects in genes encoding _______.
A
[contractile proteins]
