HLA Flashcards
1
Q
HLA
A
On chr6
2
Q
A/B/C
A
Class 1 antigen
3
Q
DP/DQ/DR
A
Class 2 antigen
4
Q
HLA B27
A
Ank spond
Postgonoccoccal arthritis
Acute anterior uveitis
Reiter’s syndrome (reactive arthritis)
5
Q
HLA DR2
A
Narcolepsy
Goodpastures syndrome
6
Q
HLA DR3
A
AI hepatitis Primary biliary cirrhosis Type 1 DM Dermatitis herpetiformis Coeliac (95% assoc HLA DQ2) Primary sjorgren syndrome
7
Q
HLA DR4
A
RA (70% patients)
More strongly 90% in Felty’s syndrome (RA, splenomegaly and neutropenia)
Type 1 DM (>DR3)
8
Q
HLA B47
A
21- hydroxylase deficiency
9
Q
HLA A3
A
Haemachromatlsis
10
Q
HLA B5
A
Bechet’s disease
