HIV-AIDS Flashcards
COVID 19 uses _____ receptor
ACE-2
_____ is component of Renin-Angiotensin system (RAS) cleaving ACE-1 and ACE-2
ACE-2
Overactivation of _____ is likely to cause COVID 19 morbidity
RAS
60% of African Americans have the ____ allele and increased COVID 19 pathology
D allele
HIV transformed our understanding of the ______ system
Immune system
T/F HIV stimulated enormous progress in understanding of infectious disease, autoimmune diseases and neoplasia !
True
What is the oral disease at presentation in HIV?
Candida
T/F: The dental health professional may be the first to suspect a patient has HIV/AIDS
True
HIV damages ________ which causes oral infections
salivary glands
Is HIV curable?
No
T/F: HIV studies have advanced our understanding of genetic information, transmission and evolution. It has an unprecedented impact on human health.
True
HIV-1 has a ____ and _____ viral replication
rapid and high
Error rate of reverse transcriptase in HIV-1 converts ___ to ____
RNA to cDNA
What are the 4 groups of HIV-1?
Group M, O, N, and P
What is the major group of HIV-1?
Group M
Group__ of HIV 1 contains Subtypes A-K- new one “L” discovered•CRF0 1-72+•Unique Recombinants als
M
Which subtype of HIV-1 dominates the HIV epidemic?
Subtype C
Where is HIV most prevalent in the world?
Africa (South Africa)
In the US, what percentage of people with HIV are African American?
43%
In the US, what percentage of people with HIV are white?
26%
In the US, what percentage of people with HIV are HIspanics?
26%
In the US, how much of HIV was transmitted from Male to Male sexual contact?
67%
In the US, how much of HIV was transmitted from heterosexual sexual contact?
24%
Where did HIV-1 pandemic originate?
Congo Basin
