HIV

Question 1

Causative agent for AIDS?

Answer 1

HIV

Question 2

What family of virus does HIV come from?

a. Picornaviridae
b. Poxviridae
c. Retroviridae
d. Oligoviridae

Answer 2

c

Question 3

What is the subfamily for HIV?

a. Vicivirus
b. Lentivirus
c. Ventivirus
d. Vettivirus

Answer 3

b

Question 4

What is the Surface glycoprotein for HIV 1?

Answer 4

p120

Question 5

What is the transmembrane glycoprotein for HIV 1?

Answer 5

p41

Question 6

What is the protein for capsid in HIV 1?

Answer 6

p24

Question 7

HIV is a single stranted (+) RNA

T or F

Answer 7

T

Question 8

What is the enzyme unique to HIV?

Answer 8

Reverse transcriptase

Question 9

What is the target cell for HIV?

Answer 9

CD4 (+) T cells

Question 10

MOT?

Answer 10

Sex
Breastfeeding
Vertical transmission
Needlestick
Transfusion of infected blood

Question 11

Early stage (months-years post exposure): Asymptomatic to mild chronic lymphadenopathy

T or F

Answer 11

T

Question 12

End stage: occurrence of neoplasms and opportunistic infections

T or F

Answer 12

T

Question 13

What is the Clinical Latency period for HIV? (Years)

a. 6-9
b. 4-20
c. 7-11
d. 9-11

Answer 13

c

Question 14

A common neoplasm among AIDS patients

a. Malignant B-Cell lymphoma
b. Kaposi’s Sarcoma
c. Cytomegalosis
d. Legionnaires disease

Answer 14

b

Question 15

HIV-1= 9 Subtypes
HIV-2 = 2 Subtypes

T or F

Answer 15

T

Question 16

CD4+/CD8+ Ratio

→ Normal = 2:1
→ AIDS = 0.5:1

T or F

Answer 16

T

Question 17

Window period is 6-12 weeks or longer

T or F

Answer 17

T

Question 18

What are the serological markers for HIV 1?

a. Anti-p24
b. Anti-gp41
c. Anti-gp120
d. Anti-gp11

Answer 18

Anti-p24
Anti-gp41

Question 19

3 main classes in diagnosing HIV

→ Detection of HIV antibodies (HIV 1 and 2 antibodies)
→ Detection of HIV antigens (confirmatory via Western blot)
→ Detection and quantification of viral nucleic acids

T or F

Answer 19

T

Question 20

What is the confirmatory test for HIV?

Answer 20

Western Blot