Hepatitis Flashcards
What are the 4 forms of hepatitis?
Acute hepa
fulminant acute hepa
Subclinical hepa without haundice
Chronic hepa
Typical form associated with jaundice
a. Acute hepa
b. fulminant acute hepa
c. Subclinical hepa without haundice
d. Chronic hepa
a
Persona with detectable antibodies in serum but no reported history of hepatitis
a. Acute hepa
b. fulminant acute hepa
c. Subclinical hepa without haundice
d. Chronic hepa
c
Accompanied by hepatic inflammation and necrosis that lasts for at least 6 months
a. Acute hepa
b. fulminant acute hepa
c. Subclinical hepa without haundice
d. Chronic hepa
d
Rare form of hepatitis associated with liver failure
a. Acute hepa
b. fulminant acute hepa
c. Subclinical hepa without haundice
d. Chronic hepa
b
Infectious hepatitis, short-incubation hepatitis
a. Hepa A
b. Hepa B
c. Hepa C
d. Hepa D
e. Hepa E
a
What is the virus for Hepa A?
a. Hepadnavirus
b. Flavivirus
c. Picornavirus
d. Deltavirus
e. Hepeviridiae
c
MOT for Hepa A?
Fecal-oral route
Incubation period for Hepa A?
a. 2-6 weeks
b. 1-3 weeks
c. 2-5 weeks
d. 1-4 days
a
Hepatitis A is anicteric (means does not develop jaundice) and it’s a self limiting disease
T or F
T
Hepa A
Elevated lever enzymes and bilirubin in serum
T or F
T
Hepa A:
IgG is detectable in serum shortly after onset of fecal shedding followed by IgM within few days
T or F
F
IgM then IgG
IgM Anti-HAV – acute infection, diagnostic
IgG Anti-HAV – manifestation of immunity; indicator of past infection; remains detectable indefinitely
T or F
T
IgM anti-HAV (+)
IgG anti-HAV (-)
a. Immunity/Past infection/Recovered
b. Ongoing infection
c. Ongoing Convalescent
b
IgM anti-HAV (+)
IgG anti-HAV (+)
a. Immunity/Past infection/Recovered
b. Ongoing infection
c. Ongoing Convalescent
c
IgM anti-HAV (-)
IgG anti-HAV (+)
a. Immunity/Past infection/Recovered
b. Ongoing infection
c. Ongoing Convalescent
a
Serum hepatitis
a. Hepa A
b. Hepa B
c. Hepa C
d. Hepa D
e. Hepa E
b
What is the virus for Hepa B?
a. Hepadnavirus
b. Flavivirus
c. Picornavirus
d. Deltavirus
e. Hepeviridiae
a
MOT for Hepa B?
Transmitted through percutaneous/mucosal routes with infected blood or body fluids
→ i.e. unprotected sexual contact, sharing of infected needles, needlestick injury, etc.
Which of the following serological markers is not easily detected
a. HBsAg
b. HBcAg
c. HBeAg
d. Total and IgM Anti-HBc
e. Anti-HBe
f. Anti-HBs
g. Anti-HBc
h. HBV DNA
b
Initial detectable marker during incubation period
a. HBsAg
b. HBcAg
c. HBeAg
d. Total and IgM Anti-HBc
e. Anti-HBe
f. Anti-HBs
g. Anti-HBc
h. HBV DNA
a
An indication of an active HBC infection
a. HBsAg
b. HBcAg
c. HBeAg
d. Total and IgM Anti-HBc
e. Anti-HBe
f. Anti-HBs
g. Anti-HBc
h. HBV DNA
a
Indicated active viral replication which is reliable marker for the presence of high levels of virus
a. HBsAg
b. HBcAg
c. HBeAg
d. Total and IgM Anti-HBc
e. Anti-HBe
f. Anti-HBs
g. Anti-HBc
h. HBV DNA
c
An indicator of recent HBC infection which only detectable serologic marker during the window period
a. HBsAg
b. HBcAg
c. HBeAg
d. Total and IgM Anti-HBc
e. Anti-HBe
f. Anti-HBs
g. Anti-HBc
h. HBV DNA
g
Seen during convalescence and recovery from HBV infection
a. HBsAg
b. HBcAg
c. HBeAg
d. Total and IgM Anti-HBc
e. Anti-HBe
f. Anti-HBs
g. Anti-HBc
h. HBV DNA
More than 1 answer
e,f
First serologic evidence of convalescence
a. HBsAg
b. HBcAg
c. HBeAg
d. Total and IgM Anti-HBc
e. Anti-HBe
f. Anti-HBs
g. Anti-HBc
h. HBV DNA
e
Serologic marker of recovery and immunity
a. HBsAg
b. HBcAg
c. HBeAg
d. Total and IgM Anti-HBc
e. Anti-HBe
f. Anti-HBs
g. Anti-HBc
h. HBV DNA
f
Useful in confirming HBV infection in patients with equivocal serological results
a. HBsAg
b. HBcAg
c. HBeAg
d. Total and IgM Anti-HBc
e. Anti-HBe
f. Anti-HBs
g. Anti-HBc
h. HBV DNA
h
HBsAg: (-)
Total Anti-HBc: (-)
IgM Anti-HBc: (-)
Anti-HBs: (-)
a. Immunity due to Vaccination
b. Chronic infection
c. Immunity due to natural infection
d. Susceptible
e. Early (Asymptomatic)
f. Window period
d
HBsAg: (-)
Total Anti-HBc: (+)
IgM Anti-HBc: (-)
Anti-HBs: (+)
a. Immunity due to Vaccination
b. Chronic infection
c. Immunity due to natural infection
d. Susceptible
e. Early (Asymptomatic)
f. Window period
c
HBsAg: (-)
Total Anti-HBc: (-)
IgM Anti-HBc: (-)
Anti-HBs: (+)
a. Immunity due to Vaccination
b. Chronic infection
c. Immunity due to natural infection
d. Susceptible
e. Early (Asymptomatic)
f. Window period
a
HBsAg: (+)
Total Anti-HBc: (+)
IgM Anti-HBc: (-)
Anti-HBs: (-)
a. Immunity due to Vaccination
b. Chronic infection
c. Immunity due to natural infection
d. Susceptible
e. Early (Asymptomatic)
f. Window period
b
HBsAg: (+)
Total Anti-HBc: (-)
IgM Anti-HBc: (-)
Anti-HBs: (-)
a. Immunity due to Vaccination
b. Chronic infection
c. Immunity due to natural infection
d. Susceptible
e. Early (Asymptomatic)
f. Window period
e
HBsAg: (-)
Total Anti-HBc: (+)
IgM Anti-HBc: (+)
Anti-HBs: (-)
a. Immunity due to Vaccination
b. Chronic infection
c. Immunity due to natural infection
d. Susceptible
e. Early (Asymptomatic)
f. Window period
f
Formerly known as non-A non-B
a. Hepa A
b. Hepa B
c. Hepa C
d. Hepa D
e. Hepa E
c
What is the virus for Hepa C?
a. Hepadnavirus
b. Flavivirus
c. Picornavirus
d. Deltavirus
e. Hepeviridiae
b
MOT of Hepa C?
Blood
What is the virus for Hepa D?
a. Hepadnavirus
b. Flavivirus
c. Picornavirus
d. Deltavirus
e. Hepeviridiae
d
Patients with Hepa D already had hepa B before
T or F
T
Infection of HBV and HDV at the same time (Acute infection)
a. Superinfection
b. Coinfection
b
Chronic infection with Hepa B and Hepa D
a. Superinfection
b. Coinfection
a
A recently identified virus with a 2-9 weeks incubation and S&S fulminant hepatitis
a. Hepa A
b. Hepa B
c. Hepa C
d. Hepa D
e. Hepa E
e
MOT for Hepa E?
Oral fecal route
