History of toxicology Flashcards
What Greek word is Toxicology derived from
toxicon
what is toxicology the study of
harmful effects of chemical or physical agents on living organisms
what is an important aspect of toxicology
prediction of risk of injury to a defined population of organisms under specified circumstances
what does chronic arsenic poisoning result in
hyperpigmentation of the skin
what is arsenic incorporated into
hair and nails
what was the outbreak of arsenic poisoning in Bradford due to
accidental contamination of peppermint sweets with arsenic trioxide
what is Diethylstillboestrol
a transplacental carcinogen
what is minamata disease a result of
environmental poisoning with organic mercury
what was thalidomide orignally used to treat
morning sickness
what was released after the chemical explosion in seveso (Italy)
Dioxins
what are the symptoms of MPTP poisoning similar to
Parkinson’s disease
What is an example of an anticancer drug
Arsenic trioxide
Features of solutions of arsenic trioxide
colourless, tasteless and odourless
What did Marsh and Reinsch develop
chemical tests for arsenic poisoning
Where is chronic arsenic poisoning a major healthcare problem
Bangladesh
Are poltchlorobiphenyls persistent organic pollutants
yes
Are all substances potentially poisonous
yes
who is the founder of modern toxicology
Orfila
who wrote the oldest books on the subject of poisoning and its treatment
Nicander
Who were Cartherine Deshayes Monvoisin and Toffana of Naples
professional poisoners
what were developed from the arrow poison curare
modern neuromuscular blocking agents
What did the San people of the Kalahari use as arrow poison
extract from beetles
Who published work on occupational diseases in the 18th century
Bernadino Ramazzini
What is clinical toxicology concerned with
diagnosis and treatment of poisoning
What is another name for industrial toxicology
occupational health or medicine
who wrote about poisons and their antidotes in the 12th century
moses maimonides
What did felice fontana suggest
that toxins might target particular organs rather than have general effects on the body
who is considered the founder of occupational medicine
bernadino Ram
what was discovered in the later half of the 19th century
metabolism fo foreign chemicals
