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HISTORY Flashcards

0
Q

Time and place where smallpox became endemic

A

10th century China

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1
Q

“People can acquire immunity”

A

Thucydides (430 BC)

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2
Q

Process that involves exposing healthy people to material from the lesion caused by the disease, either by putting it under the skin or inserting powdered scabs into the nose

A

Variolation

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3
Q

Wife of British ambassador; performed variolation technique on her son to save him from smallpox

A

Lady Mary Wortley Montague

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4
Q

Developed the first vaccine for smallpox

A

Edward Jenner

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5
Q

Discovered lymphoid tissue in the small intestine

A

Peyer

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6
Q

Name of the boy tested in Edward Jenner’s experiment

A

James Phipps

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7
Q

Discovered phagocytosis

A

Ernst Haeckel

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8
Q

Father of Immunology

A

Louis Pasteur

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9
Q

Proposed the Humoral Theory of Immunity

A

Emil Von Behring and Shibasaburo Kitasata

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10
Q

“Chicken cholera bacillus” and attenuated vaccine

A

Louis Pasteur

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11
Q

Demonstration of cutaneous (delayed-type) hypersensitivity

A

Robert Koch

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12
Q

Cellular theory of immunity through phagocytosis

A

Elie Metchnikoff

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13
Q

“Father of Humoral Immunity”
“Side Chain Receptor Theory”
“Antibody formation theory”

A

Paul Ehrlich

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14
Q

Immediate hypersensitivity anaphylaxis

A

Paul Portier & Charles Richet

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15
Q

Arthur’s reaction of intermediate hypersensitivity

A

Maurice Arthus

16
Q

Antigen-antibody binding hypothesis

A

John marrack

17
Q

Development of polio vaccine

A

Salk & Sabin

18
Q

Development of vaccine against yellow fever

A

Reed

19
Q

Discovered the complement

A

Jules Bordet

20
Q

Discovered the Major Histocompatibility Complex (MHC)

A

John Doucet

21
Q

Immune genetics of MHC

A

Baruj Banascraf

22
Q 
Clonal Selection Theory 
Identification of antibody molecule 
Interferon
Human Leukocyte Antigen (HLA) 
Immunological tolerance hypothesis
A

Macfarlane Burnet

W/ frank fenner for ITH

23
Q

T cell restriction to MHC

A

Rolf Zinckernagel & Peter Doherty

24
Q

First monoclonal antibodies (w/)
Identification of genes for T cell receptor
Monoclonal Hepatitis B vaccines

A

George Köhler (w/ Cesar Milstein)

25
Q

Th1 vs. Th2 model of T helper cell function

Identification of toll-like receptor
FOXP3

A

Timothy Mosmann

26
Q

Development of papillomavirus vaccine

A

Ian Frazer

27
Q

Hemolytic Plaque Assay

A

Neil Jurne

28
Q

Immunologic Tolerance

Investigated problem to graft rejection

A

Peter Medawar

SI (8 decks)

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