Complements Flashcards by Luis Mangahas

Q

C4 and C2 are from which pathway?

A

Classical

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Q

C4b2a is from which pathway?

A

Classical

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Q

C3 is from which pathway?

A

Classical, alternative, and mannose binding

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Q

Factor B is from which pathway?

A

Alternative

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Q

C3bBb is from which pathway?

A

Alternative

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Q

C4b2a3b is from which pathway?

A

Classical, mannose binding

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Q

C3bBb3b is from which pathway?

A

Alternative, mannose binding

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Q

C5-C9 are from which pathway?

A

Classical, alternative, mannose binding

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Q

C1qrs activity

A

Binds antibody and cell surface

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Q

C4 and C2 activity

A

C4a and C2b releases into plasma

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Q

C4b2a activity

A

Cleaves C3

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Q

C3 activity

A

C3a released in plasma,

C3b combines with C4b2a in classical and factor B in alternative

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Q

Factor B activity

A

Is split into Ba and Bb, combine with C3

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Q

C3bBb activity

A

Cleaves C3

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Q

C4b2a3b activity

A

Cleaves C5

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Q

C3bBb3b activity

A

Cleaves C5

Q

C5-C9 activity

A

Cell lysis

Q

C1qrs is from which pathway?

A

Classical

Q

C1qrs other info

A

Recognition unit

Q

C4 and C2 other info

A

Activation

Q

C4b2a other info

A

C3 covertase enzyme

Q

C3 other info

A

Activation

Q

Factor B other info

A

Activation

Q

C3bBb other info

A

C3 convertase enzyme

Q

C4b2a3b other info

A

C5 convertase enzyme

Q

C3bBb3b other info

A

C5 convertase enzyme

Q

C5-C9 other info

A

Membrane attack complex