Complements Flashcards
C4 and C2 are from which pathway?
Classical
C4b2a is from which pathway?
Classical
C3 is from which pathway?
Classical, alternative, and mannose binding
Factor B is from which pathway?
Alternative
C3bBb is from which pathway?
Alternative
C4b2a3b is from which pathway?
Classical, mannose binding
C3bBb3b is from which pathway?
Alternative, mannose binding
C5-C9 are from which pathway?
Classical, alternative, mannose binding
C1qrs activity
Binds antibody and cell surface
C4 and C2 activity
C4a and C2b releases into plasma
C4b2a activity
Cleaves C3
C3 activity
C3a released in plasma,
C3b combines with C4b2a in classical and factor B in alternative
Factor B activity
Is split into Ba and Bb, combine with C3
C3bBb activity
Cleaves C3
C4b2a3b activity
Cleaves C5