Histoplasmosis - Hongos Flashcards

1
Q

Que variedades hay? De que zonas son endémicos?

A
  • capsulatum y duboisii (África ecuatorial)
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2
Q

Donde se encuentran?

A

Suelos ricos en nitrógeno

  • excrementos de ave y murciélagos
  • cuevas
  • sitios de construcción

MUY CONTAGIOSO

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3
Q

Px sintomáticos o asintomáticos?

A

Mayoría asintomático (90%)

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4
Q

Mayor riesgo en _____ (3)

A

inmunocomprometidos, VIH y niños

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5
Q

Conversión a ______ en _____ y ____

A

Conversión a levaduras en macrofagos y neutrofilos

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6
Q

Tasa de ataque del ___

A

100% (depende del inoculo)

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7
Q

Que causa? (3)

A
  • cuadro pseudogripal con fiebre
  • histoplasmosis pulmonar
  • enf diseminada
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8
Q

Cuadro pseudogripal con fiebre (2)

A
  • linfadenopatia hiliar
  • remisión espontánea
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9
Q

Histoplasmosis pulmonar

A

Cavidades apicales y fibrosis

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10
Q

Enf diseminada (3)

A
  • crónica, subaguda o aguda
  • úlceras orales y hepatoesplenomegalia
  • muerte en 2-24 meses
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11
Q

Que órganos afecta la enf diseminada? (2)

A
  • afección a médula ósea y citopenias
  • glándulas adrenales, válvulas cardiacas y SNC
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12
Q

Dx (4)

A
  • microscopia directa (levaduras intracelulares)
  • cultivo
  • histoplasmosis
  • Ag y Ac
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13
Q

Tx

A

1-2 años

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14
Q

Estructura

Forma filamentosa

A

Macroconidias esféricas espiculares

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15
Q

Estructura

Levadura

A
  • intracelular
  • gemación
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