HISTOPATH DAY 3 Flashcards by Caleila Penn F. Esturco

ACTIVE ELEMENTS,TUMOR CELLS, TUMOR ITSELF
PROLIFERATING PART OF TUMOR HAT MADE UP OF CANCER CELL

PARENCHYMA

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CONNECTIVE TISSUE FRAMEWORK
SUPPORT THE GROWTH AND PROTECT OF PARENCHYMA MADE UP OF CONNECTIVE TISSUE AND BLOOD VESSEL

STROMA

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TUMOR DERIVED FROM MORE THAN ONE GERM AYER
TUMOR WITH NORMAL TIISUE OR ORGAN COMPONENTS THAT ARE INAPPROPRIATE TO SURROUNDING TISSUES MAY CONTAIN HAIR, TEETH, BONES,AND VERY RARELY EYEBALLS TORSO AND HANDS

TERATOMA

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TUMOR THAT DERIVES FROM MULTIPLE TISSUE TYPES

MIXED TUMORS

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EXTENT TO WHICH NEOPLASTIC CELLS ARE COMPARABLE TO NORMAL CELLS, BOTH MORPHOLOGICALLY AND FUNCTIONALLY

DIFERRENTIATION

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TUMOR IMPLANTS DISCONTINOUS WITH THE PRIMARY TUMOR
MOST RELIABLE FEATURE OF MALIGNANCY

METASTASIS

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MALIGNANT CELLS SEEDING WITHIN BODY CAVITIES; NEOPLASM PENETRATES INTO NATURAL FIELD MOST OFTEN IN THE :

PERITONEAL CAVITY

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MOST COMMON PATHWAY FOR CARCINOMAS:

LYMPHATIC SPREAD

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MOST COMMON PATHWAY FOR SARCOMAS

HEMATOGENOUS SPREAD

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THESE TWO ORGANS THAT ARE FREQUENTLY INVOLVR IN METASTASIS

LIVER AND LUNGS

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BASED ON THE SIDE OF THE PRIMARY LESION , EXTENT OF SPREAD TOO REGIONAL LYMPH NODES, PRESENCE OR ABSENCE OF METASTASIS

STAGING

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2 MAJOR AGENCES CONCERNED WITH THE STAGING OF MALIGNATN DISEASE ARE:

UICC
AJCC

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DEVELOPED BY UICC AND APPLICABLE TO ALL FORMS OF NEOPLASIA

TMN SYSTEM CANCER STAGING

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WHAT TYPE OF CANCER DES HPV CAUSE?

WARTS, SQ CELL PAPILLOMA,CERVICAL CA

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WHAT TYPE OF CANCER DES EBV CAUSE?

NASOPHARYNGEAL CA

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WHAT TYPE OF CANCER DES HEPA B CAUSE?

HEPATOCELLULARA CA

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WHAT TYPE OF CANCER DES H. PYLORI CAUSE?

GASTRIC CA OR GARSTRIC LYMPHOMA

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WHAT ARE THE 5 LABORATORY DIAGNOSIS IN CANCER

HISTIOLOGICAL AND CYTOLOGICAL METHODS
IMMUNOHISTOCHEMISTRY
MOLECULAR DIAGNOSIS
FLOW CYTOMETRY
TUMOR MARKERS

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MICROSCOPIC EXAMINATION OF CELLS FROM DIFFERENT BODY SITES

DIAGNOSTIC CYTOLOGY

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BRANCH OF GENERAL CYTOLOGY
MICROSCOPIC STUDY OF CELLS THAT HAVE BEEN DESQUAMATED FROM EPITHELIAL SURFACE

EXFOLIATIVE CYTOLOGY

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WHAT ARE THE POSSIBLE INFECTION FOUND IN EXFOLIATIVE CYTOLOGY

GONORRHEA
Chylamidia
CLUE CELLS
WARTZ
TRICHOMONAS

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SPECIMEN FOR EXAMINATIONS IN CYTOLOGY

VAGINAL SMEAR
ENDOMETRIAL AND ENDOCERVICAL SMEAR
PROSTATIC AD BREAST SECRETIONS
GASTRIC OR BRONCHIAL SECRETIONS
PLEURAL AND PERITONEAL FLUIDS
SPUTUM
SMEARS OF URINE SEDIMENTS
CSF

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FIXATIVE FOR ALL TYPES OF EFFUSION

50% ALCOHOL

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FIXATIVE FOR FOR PLEURAL AN PERITONEAL FLUID

50%

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FIXATIVE FOR SPUTUM

70% ALCOHOL

FIXATIVE FOR URINE, BRONCHIAL AND GASTRIC

95%

WHAT DOES SACCOMANO’S FIXATIVE CONTAINS?

50% ETHANOL AND 2% CARBOWAX

WHO MANY RPM AND MINUTES OF CENTRIFUGATION NEEDED?

2000 RPM FOR 2 MINS

AFTER CENTRI WHAT WILL YOU DO FOR SUPERNATANT

DECANT

AFTER CENTRI WHAT WILL YOU DO WITH THE SEDIMENTS?

SMEAR/ CELL BLCOK

WHAT FIXATIVE IS COMMONLY USED FOR SMEAR?

95% ETHANOL

WHAT IS THE BEST FIXATIVE FOR SMEAR SPX?

EQUAL PART OF 95% ETHANOL AND ETHER

WHAT IS THE BEST FIXATIVE FOR SMEAR SPX?

EQUAL PART OF 95% ETHANOL AND ETHER

IN SPRAY FIXATIVE THE SLIDE SHOULD BE KEPT DISTANCE OF __ FROM THE SPRAY

1 FOOT

HOW MANY SPECIMENS IN SPUTUM U NEED TO OBTAIN?

3 CONSECUTIVE MORNING SPUTUM

WHAT FIXATIVE YOU SHOULD USED FOR SPUTUM SPX?

SACCOMANO’S FIXATIVE

INHALATION OF AERSOL SOLUTION FOR 20MINS

SOUTUM INDUCTION

WHAT SHOULD YOU FOUND IN SPUTUM SPX TO PROVE THAT IT IS FROM DEEP COUGH?

ALVEOLAR MACHROPHAGE

HOW CAN YOU SAY THAT THE SPUTUM SPX IS ONLY SALIVA?

ABSENCE OF ALVEOLAR MACROPHAGES

PERFORMED IN PX WITH AIDS TO RLE OUT P. CARINII

BAL

SPECIMEN IS DIRECTLY SMEARED ONTO 2 LABELED SLIDE

BRONCHIAL WASHING

THIS SPECIMEN IS JELLY. LIKE CLOT

PERITONEAL, PLEURAL, PERCARDIAL FLUIDS

HOW CAN YOU PREVENT. A JELLY LIKE CLOT IN THE SPECIMEN?

ADDING 300 UNITS OF HEEPARIN PER 100 ML OF ASPIRATES

COLLECTION IS USUALLY DONE TO EXCLUDE THE POSSIBILITY OF MALIGNANT TUMORS

GASTROINTESTINAL SPECIMENS

WHAT IS PREFERRED SPECIMEN FOR URINE ?

2ND VOIDED MORNING URINE

WHAT IS THE MAJO GOAL FOR URINE SPX?

DIAGNOSIS OF URETHRAL MALIGNANCY

IS PROSTATIC FOUND IN URINE SPECIMEN?

RARELY

HOW MANY ML OF URINE IS NEEDED FOR DIAGNOSTIC CYTOLOGY?

50ML

WHAT. IS THE PREFFERED SPECIMEN FOR MALES IN URINE?

VOIDED URINE

WHAT IS THE PREFFERED URINE SPECIMEN FOR FEMALES AND WHY?/

CATHETERIZED URINE SPX TO PREVENT CONTAMINATION WITH VULVAR CELLSS

3 METHODS OF PREPARATION OF CELL BLCOK

DIRECT FILTRATION PLASMA THROMBIN CARBOWAX METHID

WHAT KIND OF METHOD IS THIS: CENTRI THE FLUID THE OBTAIN SEDIMENT AND ADD 10% FORMALIN?

DIRECT FILTRATION

WHAT KIND OF METHOD IS THIS: CENTRI— OBTAIN SEDIMENT —- ADD 1ML OF PLASMA —- ADD THROMBIN —THIS WILL FORM GEL LIKE SUBSTANCES —- PLACE N A FILTER PAPER AND ADD 10% formalin

PLASMA THROMBIN

X WHAT KIND OF METHOD IS THIS: CENTRI—OBTAIN SEEDDIMENT AND ADD CARBOWAX PLACE IN A PARAFFIN BLOCK

CARBOWAX METHOD

SCREENING TOOL FOR DETERMINATION OF CA , NOT DAIGNOSTIC

CARBOWAX METHOD

GYNECOLOGICLA SPECIMEN USEDD FOR CARBOWAX METHOD

PAP SMEARS

WHAT ARE THE SPECIMEN REQUIRING ADDITION OF AN ADHESIVE AGENT?

URINARY SEDIMENT BRONCHIAL LAVAGE SPX THAT UTILIZES PROTEOLYTIC ENZYME DURING. PROCESSING (TRYOSIN, CONCENTRATED SPUTUM AND EZNZYMATIC LAVAGE SPECIMEN FROM THE GIT

NOT RECOMMENDED AS AN ADHESIVE AGENT SINCE IT MAY RETAIN THE STAIN EOSINIC AZURE

EGG ALBUMIN

WHAT ARE THE 2 CHARACTERISTICS OF ADHESIVE AGENTS?

IT MUST BE PERMEABLE TO BOTH FIXATIVE AND STAIN IT MUST NOT RETAIN THE STAIN

RELATIVE INEXPENSIVE MAY BE PERFORMED REGULARLY EVEN IN PREGNANT WITHOUT UNDUE RISK

VAGINAL HORMONAL CYTOLOGY

RELATIVE INEXPENSIVE MAY BE PERFORMED REGULARLY EVEN IN PREGNANT WITHOUT UNDUE RISK

VAGINAL HORMONAL CYTOLOGY

VAGINAL SMEAR FOR SUCH PURPOSE ARE TAKEN FROM THE ______ OF THE VAGINAL WALL

UPPER/LATERAL THIRD

MOST SENSITIVE TO HORMONAL STAGES

UPPER/LATERAL THIRD OF THE VAGINA WALL

WHERE DOES THE T ZONE CAN BE FOUND?

BETWEEN ECTOCERVIX AND ENDOCERVIX

WHERE DOES THEE CANCER CELL ARISE?

T ZONE

THE PATIENT THAT. WILL UNDERGONE VAGINAL SMEAR SHOULD NOT BE DOUCHED OR UNDERGONE VAGINAL EXAMINATION FOR ______ BEFORE SMEARS ARE PREPARED

24-48 HOURS

WHAT SCRAPING MATERIAL IS RECOMMENDED ONLY FOR HORMONAL STUDIES?

WOODEN SPATULA

VAGINAL SMEAR SHOULD BE SPREAD ___ IN A ___ MOTION

THINLY ROTARY

TRUE OR FALSE VAGINAL SMEAR IS USED AND METHOD OF CHOICE FOR DETECTION OF FEMALE GENITAL CANCE, COMBINED VAGINAL AND CERVICAL SMEAR

TRUE

TMN USED FOR PRIMARY TUMOR

THIS USED TO DIFFERENTIATE WITH INCREASING SIZE OF THE PRIMARY TUMOR

T1\0-T1-T2-T3

IT IIS USED FOR REGIONAL LYMPH NODE INVOLVEMENT

USED FOOR INDICATION OF PROGRESSIVELY ADVANCING. NODAL DISEASSE

N0-N1

USED TO KNOW WHETHER THERE ARE DISTANT METASTASES

M0, M1

3 CARINOGENIC AGENTS

CHEMICAL RADIANT ONCOGENIC VIRUSES/ MICROBES

WHAT RA IS THE NATIONAL BLOOD SERVICES ACT OF 1994

ra7719

When was the ra7719 approved?

MAY 5 1994

AN ACT REGULATING THE COLLECTION, PROCESSING AND SALE OF HUMAN BLOOD AND THE ESTABLISHMENT AND OPERATION OF BLOOD BANKS AND BLOOD PROCESSING LABORATORIES

RA 1517

THE FIRST LAW IN THE PH THAT REGULATED THE COLLECTION, PROCESSING AND SALE OF HUMAN BLOOD AND OTHER BLOOD PRODUCT

RA 1517

PROVISION OF WHOLE BLOOD AND PRBCS STORAGE, ISSUANCE AND TRANSPORT AND DISTRIBUTION OF PRBC AND WB

BLOOD STATION

COLLECTION OF BOOD , TRANSPORT OF BLOOD CENTERS FORPROCESSING OF COMPATIBILITY TESTING OF RED CELL ONLY DOES NOT SELL, STORE AND TEST FOR TTIS

BLOOD COLLECTION UNIT

COLLECTION OF BLOOD FROM QUALIFIED BLOOD DONORS TEST FOR TTIS STORAGE, ISSUANCE, TRANSPORRTTT AND DISTRIBUTION OF UNITS TOO HELATH FACILITIES

BLOOD CENTER

STORAGE AND ISSUANCE OF WHOLE BLOOD AND BLOOD COMPONENTS OOBTAINED FROM A BLOOD CENTER CANNOT PERFORMED BLOOD COLLECTION

HOSPITAL BASED BLOOD BANK

VALIDITY OF LTO OF BLOOD SERVICES FACILITIES

3 YEARS

LAB THAT CONFIRMS OR REACTIVE EBLOOD AND BLOOD COMPONENTS

RITM

WHAT ARE THE TTI MARKERS FOR BLOOD AND BLOOD PRODUCTS

HEPA B, HEPA C, HIV 1/2, SYPHILIS, MALARIA

PHILIPPINE AIDS PREVENTION AND CNTROL ACT OF 1998

RA 8504

WHEN WAS THE RA 8504 APPROVED?

FEB 13 1996

COMPULSARY HIV TESTING SHPULD BE CONSIDERED UNLAWFUL EXCEPT:

PERSON IS CHARGED WITH CRIME PUNNISHABLE HIV STATUS IS NECESSART TO RESOLVE THE RELEVANT ISSUES UNDER EO 309 COMPLYING FOR. IRGAN DONATION ACT AND NATIONAL BLOOD SERVICE ACT

THE RIGHT OF PRIVACY OF INDIVIDUAL WITH HIV SHALL BE GUARANTEED EXCEPT:

COMPLYING. WIITH THE REPORTORIAL REQUIREMENTS IN CONJUNCTION WITH AIDSWATCH INFORMING HCW DIRECTLY INVOLVED IN THE TREATMENT OR CARE OF A PERSON WITH HIV LEGAL PROCEEDING RESPONDING TO SUBPOERNA

WHAT IS THE TTLE OF SECTION 32 IIN RA 8504

RELEASE OF HIV/. AIDS RESULTS

ALL RESULTS SHOULD BE RELEASE ONLY TO THE FOLLOWING

CLIENT. PARENT OF THE MNOR LEGAL GUARDIAN OF INSANE PERSON OR ORPHANS JUSTICE OF THE COURT OF APPEALS

WHAT IS THE TITLE OF SECTION 34 ON RA 8504

DISCLOSURE TO SEXUAL PARTNERS

WHAT. IS THE TITLE OF ARTICLE VIII

THE PHILIPPINE NATIONAL AIDS COUNCIL

UNDER RA 11166 AGE FOR CONSENT IS —-

15-17 YEARS OLD

COMPREHENSIVE DANGEROUS DRUGS ACT OF 2002

RA9165

TRACKS THE PERSONNEL WHO HANDLED THE SPECIMEN FORM THE TIME. OF COLLECTION TO IT DISPOSAL

CHAIN OF CUSTODY

LEVEL OF CONCENTRATION THAT DETERMINES WHETHER THE SPECIMEN IS POSITIVE OR NEGATIVE FOR THE ANALYTE BEING TESTED

CUT OF VALUES

WHO CAN BE THE HEAD OF THE SCREENING LAB FOR DRUG TESTING

PHYSICIAN CHEMIST MEDTECH PHARMACIST CHEM ENGINEER

WHO CAN BE THE HEAD OF THE CONFIRMATORY LAB FOR DRUGS

PHYSICIAN CHEMIST

WHO CAN BE THE ANALYST FOR SCREENING LAB OF DRUG TESTING.

CHEMIST, MT, PHARMACIST, CHEMICAL ENG

WHO CAN BE THE ANALYST FOR CONFIRMATORY LAB OF DRUG TESTIN

CHEMIST, MT PHARMACIST, CHEM ENG.

VALIDITY OF TESTS RESULT FOR SCREENING LAB ?

1 YEAR

VALIDITY OF TESTS RESULT FOR CONFIRMATORY LAB ?

1 YEAR

VALIDITY OF. CERTIFICATE ACCREDITATION FOR SCREENING LAB

2 YEARS

VALIDITY OF. CERTIFICATE ACCREDITATION FOR CONFIRMATORY LAB

1 YEAR

SPECIMEN STOAGE FOR NEGATIVE RESULT OF DRUG TESTING?

5 DAYS

SPECIMEN STOAGE FOR POSITIVE RESULT OF DRUG TESTING?

15 DAYS

SPECIMEN STOAGE FOR JUDICIAL PROCEEDING UPON REQUEST RESULT OF DRUG TESTING?

1 YEAR

NEWBORN SCREENING ACT OF 2004

RA 9288

NEWBORN SCREENING FOR THE FOLLOWING DISORDER SHOULD BE TESTED ____ AFTER BIRTH TO WITHIN ____

24 HRS 3 DAYS

IF THE NEONATE IS IN THE NIICU, MUST BE DONE WITHIN

3 DAYS

WHAT DOH MEMORANDUM ORDER # STATE THE INCLUSION OF MSUD

DOH MEMORANDUM # 2012- 0154

WHAR ARE THE DISORDER TESTING FOR NEWBORN SCREENING

CONGENITAL HYPOTHYROIDISM CONGENITAL ADRENAL HYPERPLASIA GALACTOSEMIA PKU G6PD DEFICIENCY MSUD

MOST COMMON IEM IN THE PHILIPPINES

MSUD