HISTOPATH DAY 3 Flashcards
ACTIVE ELEMENTS,TUMOR CELLS, TUMOR ITSELF
PROLIFERATING PART OF TUMOR HAT MADE UP OF CANCER CELL
PARENCHYMA
CONNECTIVE TISSUE FRAMEWORK
SUPPORT THE GROWTH AND PROTECT OF PARENCHYMA MADE UP OF CONNECTIVE TISSUE AND BLOOD VESSEL
STROMA
TUMOR DERIVED FROM MORE THAN ONE GERM AYER
TUMOR WITH NORMAL TIISUE OR ORGAN COMPONENTS THAT ARE INAPPROPRIATE TO SURROUNDING TISSUES MAY CONTAIN HAIR, TEETH, BONES,AND VERY RARELY EYEBALLS TORSO AND HANDS
TERATOMA
TUMOR THAT DERIVES FROM MULTIPLE TISSUE TYPES
MIXED TUMORS
EXTENT TO WHICH NEOPLASTIC CELLS ARE COMPARABLE TO NORMAL CELLS, BOTH MORPHOLOGICALLY AND FUNCTIONALLY
DIFERRENTIATION
TUMOR IMPLANTS DISCONTINOUS WITH THE PRIMARY TUMOR
MOST RELIABLE FEATURE OF MALIGNANCY
METASTASIS
MALIGNANT CELLS SEEDING WITHIN BODY CAVITIES; NEOPLASM PENETRATES INTO NATURAL FIELD MOST OFTEN IN THE :
PERITONEAL CAVITY
MOST COMMON PATHWAY FOR CARCINOMAS:
LYMPHATIC SPREAD
MOST COMMON PATHWAY FOR SARCOMAS
HEMATOGENOUS SPREAD
THESE TWO ORGANS THAT ARE FREQUENTLY INVOLVR IN METASTASIS
LIVER AND LUNGS
BASED ON THE SIDE OF THE PRIMARY LESION , EXTENT OF SPREAD TOO REGIONAL LYMPH NODES, PRESENCE OR ABSENCE OF METASTASIS
STAGING
2 MAJOR AGENCES CONCERNED WITH THE STAGING OF MALIGNATN DISEASE ARE:
UICC
AJCC
DEVELOPED BY UICC AND APPLICABLE TO ALL FORMS OF NEOPLASIA
TMN SYSTEM CANCER STAGING
WHAT TYPE OF CANCER DES HPV CAUSE?
WARTS, SQ CELL PAPILLOMA,CERVICAL CA
WHAT TYPE OF CANCER DES EBV CAUSE?
NASOPHARYNGEAL CA
WHAT TYPE OF CANCER DES HEPA B CAUSE?
HEPATOCELLULARA CA
WHAT TYPE OF CANCER DES H. PYLORI CAUSE?
GASTRIC CA OR GARSTRIC LYMPHOMA
WHAT ARE THE 5 LABORATORY DIAGNOSIS IN CANCER
HISTIOLOGICAL AND CYTOLOGICAL METHODS
IMMUNOHISTOCHEMISTRY
MOLECULAR DIAGNOSIS
FLOW CYTOMETRY
TUMOR MARKERS
MICROSCOPIC EXAMINATION OF CELLS FROM DIFFERENT BODY SITES
DIAGNOSTIC CYTOLOGY
BRANCH OF GENERAL CYTOLOGY
MICROSCOPIC STUDY OF CELLS THAT HAVE BEEN DESQUAMATED FROM EPITHELIAL SURFACE
EXFOLIATIVE CYTOLOGY
WHAT ARE THE POSSIBLE INFECTION FOUND IN EXFOLIATIVE CYTOLOGY
GONORRHEA
Chylamidia
CLUE CELLS
WARTZ
TRICHOMONAS
SPECIMEN FOR EXAMINATIONS IN CYTOLOGY
VAGINAL SMEAR
ENDOMETRIAL AND ENDOCERVICAL SMEAR
PROSTATIC AD BREAST SECRETIONS
GASTRIC OR BRONCHIAL SECRETIONS
PLEURAL AND PERITONEAL FLUIDS
SPUTUM
SMEARS OF URINE SEDIMENTS
CSF
FIXATIVE FOR ALL TYPES OF EFFUSION
50% ALCOHOL
FIXATIVE FOR FOR PLEURAL AN PERITONEAL FLUID
50%
FIXATIVE FOR SPUTUM
70% ALCOHOL
FIXATIVE FOR URINE, BRONCHIAL AND GASTRIC
95%
WHAT DOES SACCOMANO’S FIXATIVE CONTAINS?
50% ETHANOL AND 2% CARBOWAX
WHO MANY RPM AND MINUTES OF CENTRIFUGATION NEEDED?
2000 RPM FOR 2 MINS
AFTER CENTRI WHAT WILL YOU DO FOR SUPERNATANT
DECANT
AFTER CENTRI WHAT WILL YOU DO WITH THE SEDIMENTS?
SMEAR/ CELL BLCOK
WHAT FIXATIVE IS COMMONLY USED FOR SMEAR?
95% ETHANOL
WHAT IS THE BEST FIXATIVE FOR SMEAR SPX?
EQUAL PART OF 95% ETHANOL AND ETHER
WHAT IS THE BEST FIXATIVE FOR SMEAR SPX?
EQUAL PART OF 95% ETHANOL AND ETHER
IN SPRAY FIXATIVE THE SLIDE SHOULD BE KEPT DISTANCE OF __ FROM THE SPRAY
1 FOOT
HOW MANY SPECIMENS IN SPUTUM U NEED TO OBTAIN?
3 CONSECUTIVE MORNING SPUTUM
WHAT FIXATIVE YOU SHOULD USED FOR SPUTUM SPX?
SACCOMANO’S FIXATIVE
INHALATION OF AERSOL SOLUTION FOR 20MINS
SOUTUM INDUCTION
WHAT SHOULD YOU FOUND IN SPUTUM SPX TO PROVE THAT IT IS FROM DEEP COUGH?
ALVEOLAR MACHROPHAGE
HOW CAN YOU SAY THAT THE SPUTUM SPX IS ONLY SALIVA?
ABSENCE OF ALVEOLAR MACROPHAGES
PERFORMED IN PX WITH AIDS TO RLE OUT P. CARINII
BAL
SPECIMEN IS DIRECTLY SMEARED ONTO 2 LABELED SLIDE
BRONCHIAL WASHING
THIS SPECIMEN IS JELLY. LIKE CLOT
PERITONEAL, PLEURAL, PERCARDIAL FLUIDS
HOW CAN YOU PREVENT. A JELLY LIKE CLOT IN THE SPECIMEN?
ADDING 300 UNITS OF HEEPARIN PER 100 ML OF ASPIRATES
COLLECTION IS USUALLY DONE TO EXCLUDE THE POSSIBILITY OF MALIGNANT TUMORS
GASTROINTESTINAL SPECIMENS
WHAT IS PREFERRED SPECIMEN FOR URINE ?
2ND VOIDED MORNING URINE
WHAT IS THE MAJO GOAL FOR URINE SPX?
DIAGNOSIS OF URETHRAL MALIGNANCY
IS PROSTATIC FOUND IN URINE SPECIMEN?
RARELY
HOW MANY ML OF URINE IS NEEDED FOR DIAGNOSTIC CYTOLOGY?
50ML
WHAT. IS THE PREFFERED SPECIMEN FOR MALES IN URINE?
VOIDED URINE
WHAT IS THE PREFFERED URINE SPECIMEN FOR FEMALES AND WHY?/
CATHETERIZED URINE SPX
TO PREVENT CONTAMINATION WITH VULVAR CELLSS
3 METHODS OF PREPARATION OF CELL BLCOK
DIRECT FILTRATION
PLASMA THROMBIN
CARBOWAX METHID
WHAT KIND OF METHOD IS THIS:
CENTRI THE FLUID THE OBTAIN SEDIMENT AND ADD 10% FORMALIN?
DIRECT FILTRATION
WHAT KIND OF METHOD IS THIS: CENTRI— OBTAIN SEDIMENT —- ADD 1ML OF PLASMA —- ADD THROMBIN —THIS WILL FORM GEL LIKE SUBSTANCES —- PLACE N A FILTER PAPER AND ADD 10% formalin
PLASMA THROMBIN
X WHAT KIND OF METHOD IS THIS: CENTRI—OBTAIN SEEDDIMENT AND ADD CARBOWAX PLACE IN A PARAFFIN BLOCK
CARBOWAX METHOD
SCREENING TOOL FOR DETERMINATION OF CA , NOT DAIGNOSTIC
CARBOWAX METHOD
GYNECOLOGICLA SPECIMEN USEDD FOR CARBOWAX METHOD
PAP SMEARS
WHAT ARE THE SPECIMEN REQUIRING ADDITION OF AN ADHESIVE AGENT?
URINARY SEDIMENT
BRONCHIAL LAVAGE
SPX THAT UTILIZES PROTEOLYTIC ENZYME DURING. PROCESSING (TRYOSIN, CONCENTRATED SPUTUM AND EZNZYMATIC LAVAGE SPECIMEN FROM THE GIT
NOT RECOMMENDED AS AN ADHESIVE AGENT SINCE IT MAY RETAIN THE STAIN EOSINIC AZURE
EGG ALBUMIN
WHAT ARE THE 2 CHARACTERISTICS OF ADHESIVE AGENTS?
IT MUST BE PERMEABLE TO BOTH FIXATIVE AND STAIN
IT MUST NOT RETAIN THE STAIN
RELATIVE INEXPENSIVE
MAY BE PERFORMED REGULARLY EVEN IN PREGNANT WITHOUT UNDUE RISK
VAGINAL HORMONAL CYTOLOGY
RELATIVE INEXPENSIVE
MAY BE PERFORMED REGULARLY EVEN IN PREGNANT WITHOUT UNDUE RISK
VAGINAL HORMONAL CYTOLOGY
VAGINAL SMEAR FOR SUCH PURPOSE ARE TAKEN FROM THE ______ OF THE VAGINAL WALL
UPPER/LATERAL THIRD
MOST SENSITIVE TO HORMONAL STAGES
UPPER/LATERAL THIRD OF THE VAGINA WALL
WHERE DOES THE T ZONE CAN BE FOUND?
BETWEEN ECTOCERVIX AND ENDOCERVIX
WHERE DOES THEE CANCER CELL ARISE?
T ZONE
THE PATIENT THAT. WILL UNDERGONE VAGINAL SMEAR SHOULD NOT BE DOUCHED OR UNDERGONE VAGINAL EXAMINATION FOR ______ BEFORE SMEARS ARE PREPARED
24-48 HOURS
WHAT SCRAPING MATERIAL IS RECOMMENDED ONLY FOR HORMONAL STUDIES?
WOODEN SPATULA
VAGINAL SMEAR SHOULD BE SPREAD ___ IN A ___ MOTION
THINLY
ROTARY
TRUE OR FALSE
VAGINAL SMEAR IS USED AND METHOD OF CHOICE FOR DETECTION OF FEMALE GENITAL CANCE, COMBINED VAGINAL AND CERVICAL SMEAR
TRUE
TMN USED FOR PRIMARY TUMOR
T
THIS USED TO DIFFERENTIATE WITH INCREASING SIZE OF THE PRIMARY TUMOR
T1\0-T1-T2-T3
IT IIS USED FOR REGIONAL LYMPH NODE INVOLVEMENT
N
USED FOOR INDICATION OF PROGRESSIVELY ADVANCING. NODAL DISEASSE
N0-N1
USED TO KNOW WHETHER THERE ARE DISTANT METASTASES
M0, M1
3 CARINOGENIC AGENTS
CHEMICAL
RADIANT
ONCOGENIC VIRUSES/ MICROBES
WHAT RA IS THE NATIONAL BLOOD SERVICES ACT OF 1994
ra7719
When was the ra7719 approved?
MAY 5 1994
AN ACT REGULATING THE COLLECTION, PROCESSING AND SALE OF HUMAN BLOOD AND THE ESTABLISHMENT AND OPERATION OF BLOOD BANKS AND BLOOD PROCESSING LABORATORIES
RA 1517
THE FIRST LAW IN THE PH THAT REGULATED THE COLLECTION, PROCESSING AND SALE OF HUMAN BLOOD AND OTHER BLOOD PRODUCT
RA 1517
PROVISION OF WHOLE BLOOD AND PRBCS
STORAGE, ISSUANCE AND TRANSPORT AND DISTRIBUTION OF PRBC AND WB
BLOOD STATION
COLLECTION OF BOOD , TRANSPORT OF BLOOD CENTERS FORPROCESSING OF COMPATIBILITY TESTING OF RED CELL ONLY
DOES NOT SELL, STORE AND TEST FOR TTIS
BLOOD COLLECTION UNIT
COLLECTION OF BLOOD FROM QUALIFIED BLOOD DONORS
TEST FOR TTIS
STORAGE, ISSUANCE, TRANSPORRTTT AND DISTRIBUTION OF UNITS TOO HELATH FACILITIES
BLOOD CENTER
STORAGE AND ISSUANCE OF WHOLE BLOOD AND BLOOD COMPONENTS OOBTAINED FROM A BLOOD CENTER
CANNOT PERFORMED BLOOD COLLECTION
HOSPITAL BASED BLOOD BANK
VALIDITY OF LTO OF BLOOD SERVICES FACILITIES
3 YEARS
LAB THAT CONFIRMS OR REACTIVE EBLOOD AND BLOOD COMPONENTS
RITM
WHAT ARE THE TTI MARKERS FOR BLOOD AND BLOOD PRODUCTS
HEPA B, HEPA C, HIV 1/2, SYPHILIS, MALARIA
PHILIPPINE AIDS PREVENTION AND CNTROL ACT OF 1998
RA 8504
WHEN WAS THE RA 8504 APPROVED?
FEB 13 1996
COMPULSARY HIV TESTING SHPULD BE CONSIDERED UNLAWFUL EXCEPT:
PERSON IS CHARGED WITH CRIME PUNNISHABLE
HIV STATUS IS NECESSART TO RESOLVE THE RELEVANT ISSUES UNDER EO 309
COMPLYING FOR. IRGAN DONATION ACT AND NATIONAL BLOOD SERVICE ACT
THE RIGHT OF PRIVACY OF INDIVIDUAL WITH HIV SHALL BE GUARANTEED EXCEPT:
COMPLYING. WIITH THE REPORTORIAL REQUIREMENTS IN CONJUNCTION WITH AIDSWATCH
INFORMING HCW DIRECTLY INVOLVED IN THE TREATMENT OR CARE OF A PERSON WITH HIV
LEGAL PROCEEDING RESPONDING TO SUBPOERNA
WHAT IS THE TTLE OF SECTION 32 IIN RA 8504
RELEASE OF HIV/. AIDS RESULTS
ALL RESULTS SHOULD BE RELEASE ONLY TO THE FOLLOWING
CLIENT.
PARENT OF THE MNOR
LEGAL GUARDIAN OF INSANE PERSON OR ORPHANS
JUSTICE OF THE COURT OF APPEALS
WHAT IS THE TITLE OF SECTION 34 ON RA 8504
DISCLOSURE TO SEXUAL PARTNERS
WHAT. IS THE TITLE OF ARTICLE VIII
THE PHILIPPINE NATIONAL AIDS COUNCIL
UNDER RA 11166 AGE FOR CONSENT IS —-
15-17 YEARS OLD
COMPREHENSIVE DANGEROUS DRUGS ACT OF 2002
RA9165
TRACKS THE PERSONNEL WHO HANDLED THE SPECIMEN FORM THE TIME. OF COLLECTION TO IT DISPOSAL
CHAIN OF CUSTODY
LEVEL OF CONCENTRATION THAT DETERMINES WHETHER THE SPECIMEN IS POSITIVE OR NEGATIVE FOR THE ANALYTE BEING TESTED
CUT OF VALUES
WHO CAN BE THE HEAD OF THE SCREENING LAB FOR DRUG TESTING
PHYSICIAN
CHEMIST
MEDTECH
PHARMACIST
CHEM ENGINEER
WHO CAN BE THE HEAD OF THE CONFIRMATORY LAB FOR DRUGS
PHYSICIAN
CHEMIST
WHO CAN BE THE ANALYST FOR SCREENING LAB OF DRUG TESTING.
CHEMIST, MT, PHARMACIST, CHEMICAL ENG
WHO CAN BE THE ANALYST FOR CONFIRMATORY LAB OF DRUG TESTIN
CHEMIST, MT PHARMACIST, CHEM ENG.
VALIDITY OF TESTS RESULT FOR SCREENING LAB ?
1 YEAR
VALIDITY OF TESTS RESULT FOR CONFIRMATORY LAB ?
1 YEAR
VALIDITY OF. CERTIFICATE ACCREDITATION FOR SCREENING LAB
2 YEARS
VALIDITY OF. CERTIFICATE ACCREDITATION FOR CONFIRMATORY LAB
1 YEAR
SPECIMEN STOAGE FOR NEGATIVE RESULT OF DRUG TESTING?
5 DAYS
SPECIMEN STOAGE FOR POSITIVE RESULT OF DRUG TESTING?
15 DAYS
SPECIMEN STOAGE FOR JUDICIAL PROCEEDING UPON REQUEST RESULT OF DRUG TESTING?
1 YEAR
NEWBORN SCREENING ACT OF 2004
RA 9288
NEWBORN SCREENING FOR THE FOLLOWING DISORDER SHOULD BE TESTED ____ AFTER BIRTH TO WITHIN ____
24 HRS
3 DAYS
IF THE NEONATE IS IN THE NIICU, MUST BE DONE WITHIN
3 DAYS
WHAT DOH MEMORANDUM ORDER # STATE THE INCLUSION OF MSUD
DOH MEMORANDUM # 2012- 0154
WHAR ARE THE DISORDER TESTING FOR NEWBORN SCREENING
CONGENITAL HYPOTHYROIDISM
CONGENITAL ADRENAL HYPERPLASIA
GALACTOSEMIA
PKU
G6PD DEFICIENCY
MSUD
MOST COMMON IEM IN THE PHILIPPINES
MSUD
