Histology of the URT, Paranasal Sinuses, Salivary Glands and Tongue Flashcards
What are the important components of the nasal cavity?
Vestibule
Conchae (respiratory segment)
Olfactory component
What are the important parts of the URT?
Nasal cavity
Paranasal sinuses
Nasopharynx
Oropharynx
What are the paranasal sinuses?
Sphenoid sinus in the superior and posterior portion of the nasal cavity
What separates the 2 paired chambers of the nasal cavity?
A bony and cartilaginous septum
What are paranasal sinuses?
Air filled spaces in the bones of the walls of the nasal cavity and are extensions of respiratory segment of nasal cavity.
What is the vestibule?
The first 1.5cm of conductive portion following the nostrils.
What epithelium lines the vestibules?
Stratified (multilayered) squamous epithelium (keratinised)
This part of the nasal cavity is a continuation of the skin on the face.
What exists besides epithelium at the vestibule?
Hairs that filter large particulate matter and sebaceous glands that assist with entrapment of particulate matter
What underlies the stratified squamous epithelium of the vestibules?
The dermis (which is the lamina propria layer of connective tissue)
What kind of tissue makes up the epithelium of the respiratory portion of the nasal cavity?
Pseudostratified columnar epithelium. It is also ciliated like the rest of the respiratory tract epithelium.
Other cells that are present include: Goblet cells, basal cells, brush cells, and small granule cells
What do conchae do?
They are folds of respiratory epithelium surrounding bony projections into nasal cavity which is important for:
Surface area of mucous membrane that the air must pass through.
Causes turbulence in airflow which allows more efficient conditioning of inspired air
How is epithelium of respiratory segment of nasal cavity attached to the bone underlying it?
Via the lamina propria which consists of connective tissue.
What blood vessels are located under the mucous membrane of the respiratory segment of the nasal cavity?
Cavernous bodies are formed by veins in the lamina propria
What are basal cells?
Stem cells
What are brush cells?
Cells that make up the short, blunt microvilli of the respiratory tract
What are small granule cells?
They are cells within the respiratory epithelium that contain secretory granules
Which cells produce mucous in the respiratory tract>
Goblet cells
What kind of shape are basal cells?
Cuboidal cells
Where is the olfactory segment of the nasal cavity located?
At the dome
What type of epithelium is present in the olfactory segment of the nasal cavity?
Specialised olfactory mucosa which is made up of pseudostratified columnar epithelium
What underlies the epithelium of the olfactory segment of the nasal cavity?
Lamina propria which is continuous with the periosteum of the underlying bone.
Blood + lymphatic vessels
Unmyelinated olfactory nerves
Myelinated nerves
Olfactory glands
What do olfactory glands do? How do they stain on histology slides?
They are serous protein secreting glands which stain pink due to being eosinophilic.
What cells make up epithelium of olfactory part of the nasal cavity?
Pseudostratified epithelium
No goblet cells
Olfactory cells (receptor cells)
Supporting/sustenacular cells
Basal cells
Brush cells (specialized for transduction of general sensory stimulation of mucosa)
What do olfactory cells look like?
They are receptor cells attached to bipolar neurons and non-motile cilia on the surface.
What are supporting/sustenacular cells of the olfactory part of the nasal cavity?
Columnar cells that provide mechanical and metabolic support to olfactory cells.
What is another name for bowman’s gland and what does it do?
Olfactory gland, it produces serous fluid which is delivered to olfactory surface via short ducts with cuboidal epithelium.
They are branched tubuloalveolar glands.