histology of the gall bladder Flashcards
structure and function of the gallbladder ?
a muscular sac which :
>is lined by simple columnar epithelium
(backed by a lamina propia of loose connective tissue rich in blood vessels and lymphatic vessels, a coat of smooth muscle and an outer layer of collagenous layer of adventitia
> stores bile
has a folded mucosa when empty
modifies the bile stored within it
how is bile, arriving from the liver, removed by the gall bladder ?
This is done by actively pumping Na and Cl ions from the bile into the spaces between adjacent epithelial cells. Water then follows due to the increase in osmotic pressure in these spaces, which become distended with fluid when the gall bladder is actively concentrating bile. The water is carried away, largely by the lymphatic vessels of the lamina propria.
The gall bladder is stimulated to contract and deliver bile to the duodenum, both under nervous control (chiefly vagal), and via release of the hormone cholecystokinin by endocrine cells of the duodenum when fatty food enters it
epithelium of the gall bladder ?
tall columnar epithelial cells line the gall bladder with a brushed border
what is cholecystitis ?
inflammation of the gall bladder
>gallstones can strict the cystic duct leading to expansion of the gall bladder, thickening of the muscle layers and inflammation