Histology of Immune System: Secondary Lymphoid Tissue Flashcards
What name is given to the dividing walls in lymph nodes?
Trabeculae
What cells are present in lymph nodes?
B and T lymphocytes
Reticular cells
APCs
What is the role of reticular cells?
Production of reticular fibres/network (collagen)
What is the subcapsular sinus?
Opening under the capsule which is maintained by the reticular cells
What happens in germinal centres of follicles?
Active dividing of B cells
Where are T cells found in the lymph node?
Paracortex
What is found in the medulla?
Mature B/ plasma cells
What is the space between the medullary cords called?
Medullary sinus
What is the largest lymphoid organ?
Spleen
What is the role of the spleen?
Removal of blood-borne antigens
Removal and destruction of old/defective blood cells
Site of haemopoiesis in fetus
What is the white pulp of the spleen?
Thick sleeves of lymphoid tissue
Where is the red pulp of the spleen found?
Surrounding white pulp
What is the red pulp composed of?
Venous sinuses and splenic cords
What is found in the white pulp of the spleen?
Lymphoid tissue
T cells around arteries
B cells form follicles
What is found in the red pulp pf the spleen?
Splenic sinusoids with macrophages
Splenic cords (sheets of reticular CT)
