Histology of GI Flashcards
what are the 4 basic types of tissue
- epithelial tissue
- connective tissue
- muscle tissue
- nervous tissue
Tissue definition
a group of cells that work together and perform the same function (cells + extracellular substance)
Organ definition
made up of two or more types of tissue
Gut tube layers (in to out)
- Mucosa (epithelium, lamina propria, musclularis mucosae)
- Submucosa
- Muscularis externa (inner circular, outer longitudinal)
- adventitia/serosa
Lamina propria
the loose connective tissue sitting just under the epithelium - rich in blood, lymph vessels
Oesophagus
stratified squamous NON-KERATINISED epithelium
- submucosa shows mucous glands
What type of muscle is in each third of the muscular layer of the oesophagus
upper 1/3 = skeletal
middle 1/3 = smooth + skeletal
lower 1/3 = smooth
Stomach
Simple columnar epithelium - gastric glands in mucosa above muscularis mucosae
Why does the surface epithelium of the stomach stain pale
due to presence of mucous - doesn’t hold stain well
How many layers of muscle are in the muscular externa of the stomach
three - outer longitudinal, inner circular, innermost oblique
Small intestine
simple columnar epithelium - villi, crypts of leikerkuhn, peyers patches
Duodenum
simple columnar epithelium - characteristic brunners glands in submucosa
Ileum
simple columnar epithelium - villi and peyers patches
Jejunum
simple columnar epithelium - contains enterocytes and goblet cells
Large intestine
Thick mucosa, crypts, mucous secreting cells, no villi
three main glands in GI
Salivary glands, pancreas, liver
Salivary glands
Secretory acini - roundish structure with columnar cells and nuclei at the base
Ducts seen also
Pancreas
- endocrine part - islets of langerhans (no acini)
2. exocrine part - pancreatic acini and pancreatic duct
Liver
look for honeycomb shape?
Muscularis mucosae
thin layer of smooth muscle
epithelium
type varies with functions - basement membrane supports epithelium and not penetrated by blood vessels or nerve
submucosa
collagenous supporting tissue - contains blood vessels, lymphatics and nerves
muscularis propria
consists of smooth muscle layer (inner circular and outer longitudinal) - basis for peristaltic contraction
*stomach has an additional inner oblique muscle
adventitia
loose supporting tissue - outside peritoneum
serosa
visceral peritoneum - inside peritoneum
Protective function (areas and epithelium type)
oral cavity, pharynx, oesophagus, anal canal - stratified squamous
Secretory function (areas and epithelium type)
only seen in stomach - simple columnar with tubular glands
Absorptive function (areas and epithelium type)
typical of entire small intestine - villi with short glands called crypts (brunners glands in duodenum)
Absorptive + Protective function (areas and epithelium type)
lines the whole large intestine - closely packed straight tubular glands with goblet cells