Histology COPY Flashcards
Which of the following is NOT primarily composed of connective tissue?
a. Blood
b. Bone
c. Tendon
d. Intervertebral disc
e. Myometrium
e. Myometrium
The myometrium is the muscular layer of the uterus, thus it is composed of muscle tissue
Which of the following is NOT a fibre found in connective tissue?
a. Collagen fiber
b. Elastic fibre
c. Reticular fibre
d. Purkinje fibre
e. All of the above are fibres found in connective tissue
d. Purkinje fibre
There are 3 types of connective tissue fibres: collagen, elastic, and reticular.
Purkinje fibres are specialised muscle fibres found in the heart.
Which connective tissue cell type contains properties of smooth muscle cells?
a. Fibroblast
b. Myofibroblast
c. Histiocyte
d. Plasma cell
e. Mast cell
b. Myofibroblast
Myofibroblasts contain
properties of both fibroblasts and smooth muscle cells.
Fibroblasts produce the ground subtance in connective tissue. Histiocytes are macrophages. Plasma cells are derived from B lymphocytes. Mast cells secrete histamins and heparin.
Which cell is a connective tissue macrophage?
a. Kupffer cells
b. Histiocyte
c. Dust cell
d. Langerhans cell
e. Microglia
b. Histiocyte
Kupffer cells are hepatic macrophages. Dust cells are alveolar macrophages. LAngerhans cells are macrophages in the skin. Microglia and the CNS macrophages.
Which of the following can be classified as “specialised connective tissue”?
a. Mesenchyme
b. Mucous connective tissue
c. Dense connective tissue
d. Blood
e. Loose connective tissue
d. Blood
Specialised connective tissue includes cartilage, bone, adipose tissue, blood, and haemopoietic tissue, and lymphatic tissue.
Which of the following can be classified as “embryonic connective tissue”?
a. Cartilage
b. Mucous connective tissue
d. Adipose tissue
d. Bone
e. Blood
b. Mucous connective tissue
Embryonic connective tissue includes mesenchyme and mucous connective tissue.
What type of tissue makes up the dermis of the skin?
a. Mucous connective tissue
b. Mesenchyme
c. Loose irregular connective tissue
d. Dense irregular connective tissue
e. Dense regular connective tissue
d. Dense irregular connective tissue
Irregular as it needs strength in all directions.
What type of adipose tissue tends to increase as humans age?
a. Brown adipose tissue
b. White adipose tissue
c. Unilocular adipose tissue
d. Multilocular adipose tissue
e. Both b and c
e. Both b and c
Brown adipose tissue is multilocular adipose tissue. This is present during fetal development and then decreases after birth.
White adipose tissue is unilocular adipose tissue. This type of tissue persists into adulthood.
Which of the following would be best suited to differentiate collagen fibres from other fibres?
a. Wright’s stain
b. Haematoxylin and eosin stain
c. Sudan stain
d. Silver impregnation
e. Masson’s trichrome stain
e. Masson’s trichrome stain
A peripheral blood smear would be best visualised with Wright’s stain. Haematoxylin and eosin stain is the most commonly used tissue stain for routine histological examination. Lipids are best displayed with a sudan stain. Silver impregnation, such as with a reticular stain, can be used to visualise reticular fibres. Collagen fibres can be differentiated from other fibres by staining with Masson’s trichrome stain.
Which of the following is NOT primarily composed of connective tissue?
a. Bone marrow
b. Articular cartilage
c. Heart
d. Mesenchyme
e. Fat
c. Heart
Please be aware that there is connective tissue in the heart. The blood in the heart, for example, is composed of connective tissue. The pericardium is also composed of connective tissue. However, the primary tissue composing the heart is cardiac muscle.
Which one of these cells is not a cell type routinely found in loose connective tissue?
a. Fibroblast
b. Microglia
c. Histiocyte
d. Plasma cell
e. Mast cell
b. Microglia
Microglia are supporting cells in the nervous system.
Which of the following can be classified as “specialized connective tissue”?
a. Cartilage
b. Loose connective tissue
c. Mesenchyme
d. Dense connective tissue
e. Mucous connective tissue
a. Cartilage
Specialised connective tissue includes cartilage, bone, adipose tissue, blood and haemopoietic tissue, and lymphatic tissue.
Which of the following can be classified as “connective tissue proper”?
a. Adipose tissue
b. Dense irregular connective tissue
c. Bone
d. Blood
e. Cartilage
b. Dense irregular connective tissue
Connective tissue proper consists of loose irregular connective tissue and dense connective tissue (regular and irregular).
What type of tissue is Wharton’s jelly?
a. Mucous connective tissue
b. Mesenchyme
c. Loose irregular connective tissue
d. Dense irregular connective tissue
e. Dense regular connective tissue
a. Mucous connective tissue
What type of tissue is a tendon composed of?
a. Mucous connective tissue
b. Mesenchyme
c. Loose irregular connective tissue
d. Dense irregular connective tissue
e. Dense regular connective tissue
e. Dense regular connective tissue
Dense regular as it needs strength against directional force
What does connective tissue develop from?
a. Mesothelium
b. Mesenchyme
c. Mesangial cells
d. Mesentery
e. Wharton’s jelly
b. Mesenchyme
What colour do elastic fibres stain with Verhoeff Elastic stain?
a. Red/Orange
b. Pink/red
c. Purple/Red
d. Blue/black
e. Green/blue
d. Blue/black
Verhoeff Elastic stain stains elastic fibers blue/black. Collagen stains pink/red.
Which of the following is a component of the ground substance?
a. Hyaluronic acid
b. Proteoglycans
c. Glycosaminoglycans
d. Chondroitin sulfate
e. All of the above
e. All of the above
Within connective tissue, the cells and fibres are embedded in the ground substance. The ground substance is amorphous material. It is composed of proteoglycans and glycosaminoglycans. Hyaluronic acid and chondroitin sulfate are glycosaminoglycans.
Which of the following is NOT primarily composed of connective tissue?
a. Spinal cord
b. Pubic symphysis
c. Ligament
d. Areolar tissue
e. Organ capsule
a. Spinal cord
Spinal cord is composed of nervous tissue
Which connective tissue cell type produces the ground substance in connective tissue?
a. Fibroblast
b. Myofibroblast
c. Histiocyte
d. Plasma cell
e. Mast cell
a. Fibroblast
Which connective tissue cell is derived from B lymphocytes?
a. Fibroblast
b. Myofibroblast
c. Histiocyte
d. Plasma cell
e. Mast cell
d. Plasma cell
Which of the following can be classified as “specialised connective tissue”?
a. Mesenchyme
b. Bone
c. Dense connective tissue
d. Mucous connective tissue
e. Loose connective tissue
b. Bone
Specialised connective tissue includes cartilage, bone, adipose tissue, blood and haemopoietic tissue, and lymphatic tissue.
Which of the following can be classified as “connective tissue proper”?
a. Bone
b. Blood
c. Adipose tissue
d. Loose irregular connective tissue
e. Cartilage
d. Loose irregular connective tissue
What type of connective tissue is an undifferentiated tissue found in the embryo?
a. Mucous connective tissue
b. Mesenchyme
c. Loose irregular connective tissue
d. Dense irregular connective tissue
e. Dense regular connective tissue
b. Mesenchyme
What type of tissue is a ligament composed of?
a. Mucous connective tissue
b. Mesenchyme
c. Loose irregular connective tissue
d. Dense irregular connective tissue
e. Dense regular connective tissue
e. Dense regular connective tissue
Which of the following is not associated with connective tissue?
a. Tightly packed cells
b. Extracellular fibers
c. Tissue fluid
d. Ground substance
e. None of the above; all of the above are seen with connective tissue
a. Tightly packed cells
Connective tissue consists of cells and extracellular fibres in a ground substance and tissue fluid. There is generally abundant extracellular space in connective tissue; the cells are not tightly packed.
Which of the following would be best suited to visualise lipid?
a. Wright’s stain
b. Hematoxylin and eosin stain
c. Sudan stain
d. Silver impregnation
e. Masson’s trichrome stain
c. Sudan stain
A beauty treatment for the reduction of wrinkles is the injection of hyaluronic acid into the wrinkle. What is hyaluronic acid?
a. Dermatan sulfate
b. Proteoglycan
c. Glycosaminoglycan
d. Chondroitin sulfate
e. Keratan sulfate
c. Glycosaminoglycan
ground substance is amorphous material. It is composed of proteoglycans and glycosaminoglycans. Hyaluronic acid is a glycosaminoglycan. Dermatan sulfate, chondroitin sulfate, and keratan sulfate are also glycosaminoglycans.
What type of adipose tissue tends to decrease as humans age?
a. Brown adipose tissue
b. White adipose tissue
c. Unilocular adipose tissue
d. Multilocular adipose tissue
e. Both a and d
e. Both a and d
Brown adipose tissue is multilocular adipose tissue. This is present during faetal development and then decreases after birth.
Where is the primary site for absorption of nutrients?
a. Stomach
b. Small intestine
c. Ascending colon
d. Descending colon
e. Both a and b equally
b. Small intestine
What are the finger like projections of mucosa that are seen in the small intestine?
a. Lacteal
b. Crypts of Lieberkuhn
c. Plicae circulares
d. Striated border
e. Villi
e. Villi
The lymphatic capillary within a villus of the small intestine is a lacteal.
Crypts of Lieberkuhn are the intestinal glands.
The plica circulares is a projection with a core of submucosa.
Microvilli that are seen on the epithelial cells in the small intestine form the brush border or striated border.
Villi are finger like projections of mucosa seen in the small intestine.
What is the lymphatic capillary within a villus of the small intestine called?
a. Lacteal
b. Crypts of Lieberkuhn
c. Plicae circulares
d. Striated border
e. Villi
a. Lacteal
Which layer contains the lamina propria?
a. Mucosa
b. Sub mucosa
c. Muscularis externa
d. Serosa
e. Adventitia
a. Mucosa
The mucosa is the innermost layer of the GI tract. It consists of epithelium, lamina propria, and muscularis mucosa.
Where are Peyer’s patches located?
a. Esophagus
b. Stomach
c. Small intestine
d. Large intestine
e. Rectum
c. Small intestine
Peyer’s patches are large nodules of lymphatic tissue. They are seen in the small intestine.
What type of muscle makes up the muscularis externa in the esophagus?
a. Smooth
b. Striated
c. Cardiac
d. both a and b
e. a, b, and c.
d. both a and b
The muscularis externa in the upper third of the esophagus is composed of striated muscle and in the lower third it is smooth muscle. The middle third is a blend.
What are mucous surface cells?
a. Simple squamous epithelium
b. Simple cuboidal epithelium
c. Simple columnar epithelium
d. Stratified squamous epithelium
e. Transitional epithelium
c. Simple columnar epithelium
What is another term for the brush border?
a. Lacteal
b. Crypts of Lieberkuhn
c. Plicae circulares
d. Striated border
e. Villi
d. Striated border
It is made of microvilli
Which cells secrete intrinsic factor?
a. Parietal cells
b. Oxyntic cells
c. Chief cells
c. Mucous neck cells
e. Both a and b
e. Both a and b
Chief cells secrete pepsinogen. Pepsinogen is the precursor for pepsin. Parietal cells are also called oxyntic cells. They secrete hydrochloric acid and intrinsic factor. Mucous neck cells contain mucinogen granules.
Which layer of the gastrointestinal tract contains the gut associated lymphatic tissue?
a. Mucosa
b. Submucosa
c. Muscularis externa
d. Muscularis mucosae
e. Serosa
a. Mucosa
Which layer contains Meissner’s plexus?
a. Mucosa
b. Sub mucosa
c. Muscularis externa
d. Serosa
e. Adventitia
b. Submucosa
What type of tissue lines most of the gastrointestinal tract?
a. Simple squamous epithelium
b. Simple cuboidal epithelium
c. Simple columnar epithelium
d. Stratified squamous epithelium
e. Transitional epithelium
c. Simple columnar epithelium
The lining of the gastrointestinal tract is simple columnar epithelium. Epithelium lines body cavities and surfaces. Simple columnar epithelium is “simple” because it is one cell thick. “Columnar” cells are taller than they are wide and have an oval nucleus.
What type of tissue lines the upper esophagus?
a. Simple squamous epithelium
b. Simple cuboidal epithelium
c. Simple columnar epithelium
d. Stratified squamous epithelium
e. Transitional epithelium
d. Stratified squamous epithelium