HIstology - Blood Flashcards

1
Q

blood

A

specialized CT of a fluid nature

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2
Q

blood made up of

A

plasma and blood elements

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3
Q

plasma

A

forms 55% of blood volume; made up of mostly water; great number of elements are suspended, including end products of digestion

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4
Q

Erythrocytes

A

RBCs; not true cells; appear circular, biconcave, no nucli and filled with pigment hemoglobin; diameter = 7.5-8 microns; 5-5.5 million in males; less than .5 million in females; life span = 120 days; old RBCs destroyed by phagocytes of bone marrow and spleen;

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5
Q

Erythrocyte function

A

hold and release oxygen and carbon dioxide

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6
Q

anisoctyosis

A

variation in size of RBCs; occuring in some types of anemia

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7
Q

macrocytosis

A

increase in size of RBC; ocurring in some types of anemia

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8
Q

microcytosis

A

decrease in size of RBCs; occurs in some types of amemia

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9
Q

plycythemia

A

increase in number of RBCs

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10
Q

polycythemia caused by

A

physiological or pathological

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11
Q

reduction in number of RBCs occurs in

A

certain types of anemia

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12
Q

poikilocytosis

A

variation in shape of RBCs

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13
Q

hemolysis

A

destruction of RBCs with liberation of hemoglobin

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14
Q

hemolysis caused by

A

malaria

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15
Q

Rouleaux formation

A

the phenomenon where RBCs pile in a regular row as they pass through a narrow capillary

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16
Q

Leukocytes

A

WBCs; true cells; normal count= 5,000-10,000

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17
Q

leukocytosis

A

an increase in number of WBCs

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18
Q

leukocytosis occurs because of

A

a number of infectious diseases

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19
Q

leukopenia

A

a reduction in number of WBCs

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20
Q

leukopenia occurs due to

A

inhibition of bone marrow as a result of toxic side effects of chemical or physical agents

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21
Q

leukemia

A

malignant condition of bone marrow where immature leukocytes are released into the blood and the leukocytic count shows an excessive increase

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22
Q

2 types of leukocytes

A

granular and nongranular

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23
Q

granular leukocytes

A

polymorph nuclear leukocytes with cytoplasmic granules

24
Q

3 types of granular leukocytes

A

neutrophils, eosinophils and basophils

25
Q

neutrophils

A

round with lobulated nucleus (2-5 lobes) and fine, pink granules; diameter = 10-12 microns; 60-75%

26
Q

neutrophils function

A

phagocytic

27
Q

neutrophilia

A

increase in number of neutrophils

28
Q

neutrophilia caused by

A

acute bacteria infections

29
Q

eosinophils

A

round with bilobed nucleus and coars acidophilic granules; diameter = 12-14 microns; 2-4%

30
Q

eosinphils function

A

breakdown antigen antibody complexes

31
Q

eosinophilia

A

pathological increase in eosinophils

32
Q

eosinophilia caused by

A

allergic conditions and parasitic infections

33
Q

basophils

A

round with bilobed nucleus and course basophilic granules masking the nucleus; diameter = 8-10 microns; .5-1%;

34
Q

basophils fxn

A

produce histamine and heparin

35
Q

basophilia

A

pathological increase in basophils

36
Q

basophilia caused by

A

chicken pox

37
Q

nongranular leukocytes

A

no cytoplasmic granules; agranulari leukocytes

38
Q

2 types of nongranular leukocytes

A

lymphocytes and monocytes

39
Q

lymphocytes

A

small, round with large round nucleus and little cytoplasm; diameter = 6-8 microns; 20-25%

40
Q

T - lymphocytes fxn

A

cell mediated immune responses

41
Q

B - lymphocytes fxn

A

differentiate to plasma cells which produce antibodies

42
Q

lyphocytosis

A

increase in number of lymphocytes

43
Q

lyphocytosis caused by

A

viral and fungal infections

44
Q

monocytes

A

large, round to oval with kidney shaped nucleus; diameter = 14-20 microns; 5-8%

45
Q

monocytes function

A

phagocytic

46
Q

monocytosis

A

increase in number of monocytes

47
Q

monocytosis caused by

A

malaria; increase in chronic inflammation

48
Q

thrombocytes

A

blood platelets; tiny, rounded bodies with a cental dark zone (chromomere) and outer lighter zone (hyalomere); diameter = 2-4 microns; 200,000-300,000;

49
Q

thrombocytes function

A

produce factors important in blood clotting

50
Q

thrombocytopenia

A

some drugs may supress bone marrow with depression of platelet number

51
Q

hemopoiesis

A

blood development; blood elements develop in myeloid tissue (bone marrow) and lymphoid tissue

52
Q

hemocytoblasts

A

mother of all myeloid elements; large round cells with basophilic cytoplasm; divides and differentiates

53
Q

3 daughter cells of hemocytoblast (plus two more)

A

rubriblasts, myeloblasts, megakaryoblasts; lymphoblasts and monoblasts

54
Q

rubriblast

A

mother cell of all RBCs

55
Q

myeloblasts

A

mother of granular WBCs

56
Q

megakaryoblasts

A

mother of all platelets