Histology Flashcards
functions of the kidney and urinary tract
water and electrolyte homeostasis body fluid osmolarity acid-base balance excrete waste (urea, creatinine) endocrine gland (produces renin and erythropoietin)
what is the kidney covered by?
strong fibrous capsule of dense collagen fibres
what is the functional unit of the kidney?
nephron
what structures make up the nephron?
renal corpuscle
proximal convoluted tubule
loop of Henle
distal convoluted tubule
what does the renal corpuscle produce?
glomerular filtrate
what two cell layers separate the blood and glomerular filtrate?
capillary endothelium (fenestrated) podocytes
basement membrane in between made up of GAGs
role of the PCT
reabsorption of water, protein, amino acids, carbs and glucose
what facilitates the PCT role?
extensive brush border
role of the loop of Henle
creation of hyperosmotic environment in medulla with vasa recta
role of DCT
acid-base balance
water balance
what is not part of the nephron?
collecting duct
what is the urinary tract lined by?
stratified transitional epithelium (urothelium) with umbrella cells providing an impermeable membrane
layers of the urinary tract
urothelium
lamina propria of connective tissue
2 layers of smooth muscle (inner longitudinal and outer circular)
adventitia
what happens to the smooth muscle as the ureter nears the bladder?
3 layers of smooth muscle rather than 2
how long is the urethra in females?
3-5cm
what is the female urethra lined by?
transitional which become stratified squamous epithelium
how long is the urethra in males?
20cm
three types of urethra in the male
- prostatic
- membranous
- penile
describe the prostatic urethra
3-4cm through the prostate gland
lined by transitional epithelium
describe the membranous urethra
1cm from prostate to bulb of the penis with stratified columnar epithelium
describe the penile urethra
15cm lined by stratified squamous epithelium