Histology Flashcards
Histology wise: what does the pericardium contain?
- (F) Non-elastic dense irregular connective tissue
- (PS) Connective tissue
- (VS) Mesothelium (Squamous) & Adipose tissue
How many chambers does the heart have?
The heart contains four chambers.
Whats the function of the veins?
Both atria receive blood from vessels that return blood to the heart, the VEINS.
Whats the function of the arteries?
The ventricles eject blood from the heart towards vessels that distribute it, the ARTERIES.
Which structures can we find in the right atrium? State 5
✓Auricle ✓ Pectinate muscles (anterior wall) ✓ Interatrial septum ✓ Fossa ovalis ✓ Tricuspid valve
Blood supply right atrium?
- Superior vena cava
- Inferior vena cava
- Coronary sinus
Blood supply right ventricle?
From right atrium through tricuspid valve
What structures can we find in the right ventricles? state 6
- Tricuspid valve ✓ Interventricular septum: partitions ventricles ✓Papillary muscles (trabeculae carneae) ✓ Chordae tendinae ✓ Pulmonary semilunar valve ✓ Pulmonary trunk
What strcutures do we find in the left atrium? state 4
✓ Auricle
✓ Interatrial septum
✓ Pectinate muscles (confined to auricle)
✓ Bicuspid (mitral) valve
Blood supply left atrium?
FOUR pulmonary veins
What structures can we find in the left ventricles? State 4
✓ Bicuspid valve
✓ Interventricular septum: partitionsventricles
✓ Papillary muscles (traberculae carneae)
✓ Chordae tendinae
✓ Aorta
✓ Aortic semilunar valve
Blood supply left ventricle?
✓ From left atrium through the bicuspid valve (left atrioventricular valve)
Pulmonary trunk where do they exit? (left & right pulmonary arteries)
Exit RV
Where does the Aorta exit?
Exits LV
Inferior and superior vena cava, enter
Enter RA
4 Pulmonary veins, enter:
Enter LA
Which side pumps deoxiginated blood?
The right side of the heart pumps deoxygenated blood through the pulmonary circuit towards the pulmonary alveoli
Which side pumps oxygenated blood?
The left side of the heart pumps oxygenated blood through the systemic circulation to all the body tissues except the pulmonary alveoli
Cardiac valves, histology:
Four dense connective tissue rings that surround the valves of the heart
Atrioventricular valves:
▪ Tricuspid (right side)
▪ Bicuspid or Mitral (left side)
Semilunar or Sigmoid:
▪ Pulmonary
▪ Aortic
When AV valves open: Why do they do it and which muscles are included for this process?
THIS occurs when ventricles are relaxed, chordae tendineae are slack and papillary muscles are relaxed.
When AV valves close: Why do they do it and which muscles are included for this process?
A-V valves close preventing backflow of blood into atria.
− THIS occurs when ventricles contract: blood pushes valve cusps closed; papillary muscles contract and pull taut the chordae tendineae, prevent in this way cusps from everting.
Endocardium histology
Endothelium and various connective tissue.
Myocardium Histology:
Cardiomyocytes
Epicardium histology
Visceral layer of serous pericardium.
• In humans, the subserous layer contains white
adipose tissue where the nerves and blood vessels that serve the heart are found.
With what is the endocardium is in touch?
It is the inner tunic of the heart.
• It continues with blood vessels.
Composition of the Endocardium:
- Endothelium: simple squamous epithelium, facing the internal surface of the heart.
- Subendothelial layer: connective tissue with elastic and collagen fibres, and some smooth muscle fibres.
- Subendocardial layer: blood vessels, loose connective tissue, nerves and Purkinje fibres (conducting fibres in ventricles).
What function has the myocardium?
➢ It gives volume to the heart.
➢ It is responsible for the pumping action.
Whatt kind of tissue does the myocardium have?
- It is the cardiac muscle tissue.
- It is the thickest layer of the heart.
- Cardiomyocytes in bundles.
What types of fibres does the myocardium have?
- Contractile
- Modified
What kind of conduction system does the modified include?
- Pacemaker cells
- Conduction system
- Myodendocrine cells
Pacemaker cells: What do they do?
Generate rhythmic and spontaneous action potentials. Auto rhythmic.
Conduction system: what do they do?
Internodal pathways, Bachmann bundle, and the His-Purkinje system.
Adherens junctions:
Anchor (befestigen) the actin filaments
Desmosomes
separation of cells during contraction
Gap junctions
allow ion continuity and communication (passage of ions) between adjacent cells. Synchronicity.
Contractile fibres:
- less sarcoplasmic reticulum
- myocytes form bundles
- many mitochondria
Who has myocytes?
cardiac muscle
Who has skeletal fibres?
skeletal muscle?
Who has branching fibres?
Cradiac muscle
Who has shorter and wider muscles in a square shape?
cardiac mucles
Who has not branched fibres=
skeletal muscle
Who has centrally located nucleus?
Cardiac muscles
Who has longer and cylindrical muscles?
Skeletal muscle
Who has multinucleate nucleus?
Skeletal muscles?
Who has less sarcoplasmic reticulum?
Cardiac muscles
Who has calcium for contraction that comes from extracellular fluid and sarcoplasmic reticulum=
Cardiac muscle
Who has a developed srcplasmic reticulum and calcium comes from SR?
Skeletal muscle
Who has dads?
Cardiac muscle
Whi has triads?
Skeletal muscle
Who has wider and fewer t tubules?
cardiac muscle
Who has nervous control?
Cadiac muscle
Who has a somatic nervous system?
skeletal muscle
Autorhythmic cells:
important
Fire action potentials spontaneously, act as pacemaker, and form
the conduction system of the heart.
• Sinoatrial (SA) node:
important
➢ Cluster of cells in the wall of right atrium (under the opening of the superior vena cava).
➢ Begins heart activity that spreads to both atria.
➢ Excitation spreads to atrioventricular (AV) node as well.
AV node:
important
Within interatrial septum, transmits signal to the bundle of His.
His-Purkinje system:
important
➢ The connection between atria and ventricles.
➢ His bundle divides into bundle branches (right and left) which transmit the signal to Purkinje fibers, large diameter fibers that
conduct signals quickly.
Typical cardiac fibres:
: in myocardium
Conduction fibres
from the sub endocardium to the myocardium.
Less myofibrils and more glycogen
Nodal fibres:
sinoatrial and atrioventricular nodes. Small, spindle shape, few peripheral myofibrils, able to depolarize spontaneously.
Intermediate fibres:
atrial myocardium. Transition morphology between contractile and conduction fibres
Myoendocrine fibres:
atrial myocardium. Few striations, electrodense granules which contain hormones that regulate blood pressure (natriuretic peptides).
Visceral layer of pericardium: Histoogy
mesothelium (simple squamous epithelium)
PERICARDIUM - EPICARDIUM
Visceral layer of pericardium: mesothelium (simple squamous epithelium) over areolar connective tissue and adipose tissue (it contains blood vessels, nerves, and lymphatic ganglia that supply the myocardium