Histo Lec - M9 Integumentary System Flashcards
is the outer avascular epithelial layer
epidermis
epidermis consists of what epith
keratinized stratified squamous epith
is the inner layer and consists of a dense irregular connective tissue.
dermis
is a transitional layer of loose connective and adipose tissue between the dermis and underlying structures, permitting movement between the two.
hypodermis
classified as thick or thin depending upon the thickness of the epidermis
skin
The cells of this layer are filled with keratin and devoid of all organelles. Their plasma membranes are coated with an extra-cellular lipid layer. The thickness of this stratum is variable, being thin in thin skin, thicker in thick skin and hypertrophied in calluses.
Stratum corneum
Characteristic of only thick skin, this thin layer of consists of flat, eosinophilic, enucleated cells.
Stratum lucidum
Usually 1-3 cell layers thick, the keratinocytes in this layer are flattened, nucleated cells containing basophilic keratohyalin granules
Stratum granulosum
This stratum is typically several cells thick but does vary with location. Its polygonal cells have a central nucleus and exhibit numerous cytoplasmic processes (spines) which attach to reciprocating processes of adjacent cells by desmosomes.
Stratum spinosum
This is the proliferative layer resting on the basement membrane. It consists of a single layer of cuboidal cells with sparse, basophilic cytoplasm and variable amounts of the pigment melanin
Stratum basale
thinner, more cellular, and contains small diameter reticular and type I collagen fibers.
The superficial papillary layer
lies deep to the papillary layer and is typically thicker and less cellular. It has larger diameter type I collagen and elastic fibers. In the areolae and perineum, this layer contains smooth muscle.
The reticular layer
are the most abundant cells of the epidermis. They are attached to one another by desmosomes and to the basal lamina by hemidesmosomes
Keratinocytes
are derived from neural crest cells and account for about 5% of the living cells in the epidermis
Melanocytes
account for 2-3 % of the living epidermal cells. Unlike melanocytes, these immune system cells can be found throughout the epidermis.
Dendritic cells (or Langerhans’ cells)