Histo EMQ notes

Question 1

Strep viridans, optochin sens, staph A, IVDU, dental procedures

Answer 1

Infective endocarditis

Question 2

Nutmeg liver

Answer 2

Congestive caridac failure, LV failure

Question 3

Oat shaped cells, haemoptysis, wt loss, smoking

Answer 3

Small cell carcinoma

Question 4

Apple green bifringence on congo-red stain

Answer 4

Amyloidosis

Question 5

pANCA, renal failure

Answer 5

Churg-Strauss, microscopic polyangitis

Question 6

Anti-Jo, rash around eyes, gottron papules, increased CK

Answer 6

Dermatomyositis

Question 7

Anti-Ro, anti-La, exocrine destruction

Answer 7

Sjogren’s

Question 8

Anti-centromere

Answer 8

CREST

Question 9

Anti-topoisomerase

Answer 9

Diffuse systemic scleroderma

Question 10

Transmural inflam, non caseating granuloma, skip

Answer 10

Crohn’s

Question 11

Villous atrophy, crypt hyperplasia

Answer 11

Coealiac’s

Question 12

Signet ring cells, linitis plastica, leather bottle

Answer 12

Gastric carcinoma

Question 13

Superficial continuous colonic inflammation

Answer 13

Ulcerative colitis

Question 14

Perl’s Prussian blue stain

Answer 14

Haemochromatosis

Question 15

Afloxatin exposure, aspergillus, wt loss, jaundice ascites

Answer 15

Hepatocellular carcinoma

Question 16

Autoimmune deep bullous condition

Answer 16

Pemphigoid

Question 17

Salmon pink plaques, silvery white scales

Answer 17

Psoriasis

Question 18

Solar elastosis, parakeratosis, sandpaper, warty

Answer 18

Actinic keratosis

Question 19

Haematuria, red+white cell casts, dysmorphic red cells, oliguria, HTN

Answer 19

Nephritic syndrome

Question 20

Crescent morphology on immunofluorescence

Answer 20

Rapidly progressive glomerulonephritis RPGN

Question 21

Muddy casts

Answer 21

Acute tubular necrosis

Question 22

Spike/dome protrusions, sub-epithelial immunoglobulin and granular staining pattern

Answer 22

Membranous glomerulonephritis

Question 23

Normal light microscopy, podocyte effacement on EM

Answer 23

Minimal change glomerulonephritis

Question 24

Obliterated lumen and podocyte effacementon histological examination. Not responsive to steroids

Answer 24

Focal segmental glomerulonephritis

Question 25

Breast mass artichoke like appearance

Answer 25

Phylloides

Question 26

Breast mass w/ calcification on mammogram

Answer 26

Ductal carcinoma in situ

Question 27

Peau d’orange

Answer 27

Infiltrating ductal carcinoma

Question 28

Breats feeding, erythematous, tender breast

Answer 28

Mastitis, staph A infx

Question 29

Lytic lesions around the knee, pain and ROM, giant osteoclasts surrounding ovoid and spindle cells

Answer 29

Giant cell tumour

Question 30

Cafe-au-lait, multiple #’s

Answer 30

Fibrous dysplasia

Question 31

Valvular vegetation with absence of fever

Answer 31

Non-bacterial thrombotic endocarditis

Question 32

Aortic dissection

Answer 32

Marfan’s

Question 33

Difficult to see outline of myocardial fibers

Answer 33

1-4days after acute MI

Question 34

Alpha-synuclein protein mutation

Answer 34

Familial parkinsons

Question 35

Shepard’s crook, chinese letters, soap bubble,

Answer 35

Fibrous dysplasia

Question 36

Acanthocytes/spur cells, codocytes

Answer 36

Hyposplenism

Question 37

Hyaline cartilage tumour

Answer 37

Enchondroma

Question 38

Elevated periosteum (Codman’s triangle), sunburst appearance, bone formation w/in tumour, tumour cells +ve for Alk Phos

Answer 38

Osteosarcoma, most common bone malignancy

Question 39

Onion skinning of periosteum

Answer 39

Ewing’s sarcoma

Question 40

Lung disease post trauma/burns/sepsis

Answer 40

Acute respiratory distress syndrome