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Path > Haem EMQ notes > Flashcards

Haem EMQ notes Flashcards

1
Q

Hypochromic, microcytic

A

Fe def

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2
Q

Macrocytic, hypersegmented neutrophils, malabsorption

A

Megaloblastic anaemia, B12 def

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3
Q

Pancytopenia, Infx, bruising, fatigue

A

Aplastic anaemia

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4
Q

RA/TB, microcytic, hypochromic, rouleaux

A

Anaemia of chronic disease

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5
Q

Mediterranean, microcytic, normal iron studies

A

Beta-thalassaemia

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6
Q

Direct antiglobulin test +ve

A

Autoimmune haemolytic anaemia

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7
Q

Heinz bodies, fava beans, bite cells

A

G6PD def

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8
Q

Jaundice, schistocytes

A

Microangiopathc haemolytic anaemia

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9
Q

Electrophoresis diagnostic, dactylitis, gutl-val6

A

Sickle cell anaemia

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10
Q

Rhesus -ve mother, severly jaundice baby

A

Haemolytic disease of the newborn

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11
Q

Post-splenectomy, inclusions w/in erythrocytes

A

Howell-Jolly bodies

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12
Q

Tear drop cells, dry-tap

A

Myelofibrosis

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13
Q

Cabot rings

A

Megaloblastic anaemia

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14
Q

FVIII def

A

Haemophillia A

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15
Q

FIX def

A

Haemophilia B

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16
Q

MAHA, Renal failure, Cranial, High temp + low plts

A

TTP

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17
Q

Sepsis/malignancy/trauma, reduced plt count, anaemia

A

DIC

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18
Q

High/normal APTT, low FVIII, low ristocetein

A

vWD

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19
Q

Thrombophilia where FV is unable to be degraded by protein C

A

FV Leiden

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20
Q

Anti-caridolipin Abs, lupus anticoagulant, SLE

A

Antiphospholipid syndrome

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21
Q

Corckscrew appearance on angiogram, smoking

A

Buerger’s

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22
Q

Persistence of FV+FVIII

A

Protein s def

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23
Q

Immunosupressed+bld transfusion, D, Rash

A

Graft vs Host disease

24
Q

Hx of recurrent chest+GI infx + Bld transfusion

A

IgA def

25
Q

9;22 phili

A

CML

26
Q

Tartrate-resistant acid phosphatase (TRAP)

A

Hairy cell leukaemia

27
Q

Auer rods

A

AML

28
Q

Japanese/Caribbean, Lymphocytosis, HyperCa

A

Adult T cell leukaemia

29
Q

Smudge cells, lymphocytosis >4000

A

CLL

30
Q

Starry sky

A

Burkitt’s

31
Q

B Sx’s, painful lump after ETOH, Reed-Sternberg

A

Hodgkin’s

32
Q

11;14, BCL-2

A

Mantle cell lymphoma

33
Q

Centrocytes, centroblasts, 14;18, BCL-2

A

Follicular lymphoma

34
Q

Burning finger sensation, High Plts >600

A

Essential thrombocythaemia

35
Q

Bence-Jones, lytic lesions

A

Multiple myeloma

36
Q

Monocyte >1000, myeloblast >5% peripheral bld

A

Chronic myelo-monocytic leukaemia

37
Q

Itching after hot bath, Hb >18, JAK2, V617F

A

Polycythaemia ruba vera

38
Q

<6hrs of transfusion non-cardiogenic pulmonary oedema, granulocyte aggregation

A

Transfusion related acute lung injury

39
Q

Immediately after transfusion, fever, pain in back/chest, hypotension, dark urin, DIC

A

ABO incompatibility

40
Q

> 24hrs after transfusion, already sensitized, falling Hb, fever, jaundice

A

Delayed haemolytic transfuison reaction

41
Q

Osmotic fragility test

A

Spherocytosis

42
Q

Coomb’s test +ve

A

Autoimmune haemolytic anaemia

43
Q

Schiling test

A

Vit B12 def/pernicious anaemia

44
Q

Anti-malarial tablets/sulphonamides/fava beans causing haemolytic anaemia

A

G6PD def

45
Q

Elliptocyte occuring in IDA, thalassaemia+pyruvate kinase def

A

Pencil cells

46
Q

Central dense area w/ ring of pallor in Hepatic pathology/Hyposplenism/Hbglobinopathies

A

Target cells

47
Q

Hb effect of EBV

A

Hyposplenism

48
Q

Cause of aplastic crises in SCC

A

Parvovirus B19

49
Q

Causes of colf agglutination AIHA

A

Cold LID
lymphoproliferative disease e.g. CLL lymphomas
Infections e.g mycoplasma, EBV
Don’t know/idiopathic

50
Q

Donath-Landsteiner Abs, cold weather, haematuria, jaundice

A

Paroxysmal cold haematuria

51
Q

Raised Ca, normal Alk phos, raised ESR, lytic lesions

A

MM

52
Q

<20% blasts

A

Myelodysplastic syndromes

53
Q

> 20% blasts

A

Acute leukaemia

54
Q

Polycythaemia, smoker

A

Combined Polycythaemia

55
Q

Non classical Hodgkins lymhoma

A

Nodular lymphocytic

56
Q

PML-RARA 15:17

A

Acute promyelocytic leukaemia

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