Histamine Flashcards

1
Q

Antihistamines

A

Inverse Agonist

Binds to unliganded H1 receptors and keeps them in an inactive state

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2
Q

Cimetidine

A

Peptic Ulcer Drugs

Binds to H2 receptors

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3
Q

Diphenhydramine

A

First Generation Antihistamine
Enters CNS –> Sedates

Blocks H1 and Cholinergic/Adrenergic/Serotonergic

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4
Q

Hydroxyzine

A

First Generation Antihistamine
Enters CNS –> Sedates

Not Specific
Blocks H1 and
Cholinergic/Adrenergic/Serotonergic

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5
Q

Cetirizine

A

Second/Third Generation Antihistamines
Enter CNS Less
Fewer Autonomic Effects
Less Sedating

Specific for H1

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6
Q

Loratidine

A

Second/Third Generation Antihistamines
Enter CNS Less
Fewer Autonomic Effects
Less Sedating

Specific for H1

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7
Q

Fexofenadine

A

Second/Third Generation Antihistamines
Enter CNS Less
Fewer Autonomic Effects
Less Sedating

Specific for H1

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8
Q

Levoceterizine

A

Second/Third Generation Antihistamines
Enter CNS Less
Fewer Autonomic Effects
Less Sedating

Specific for H1

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9
Q

Desloratadine

A

Second/Third Generation Antihistamines
Enter CNS Less
Fewer Autonomic Effects
Less Sedating

Specific for H1

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