Hist: Skeletal muscle and nerve tissue Flashcards

1
Q

Skeletal muscle

A

makes up the skeletal muscle system
striated and voluntary movement and posture
makes up 40 percent of the body mass

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2
Q

Cardiac muscle

A

Heart, striated and involuntary

pumps blood through the CV system

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3
Q

Smooth muscle

A

Non-striated and involuntary
visceral organ tone and movement, walls of hollow viscera, and blood vessels
does vasoconstriction and dilation

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4
Q

How does contraction occur?

A

thin (actin) microfilaments and thick (myosin) filaments organize into structures called myofibrilsin the cytopasm
when they slide past each other contraction occurs

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5
Q

what are the three layers of Connective tissue that organizes the myofibers into skeletal muscle?

A

Endomysium: separates myofibers
Perimysium: separates fascicles
Epimysium: Surrounds the entire muscle

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6
Q

Where is the nuclei located in a skeletal muscle cell

A

multinucleated cylinders

nuclei are located in the periphery of the cell and the cytoplasm is primarily occupied by myofibrils

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7
Q

What is the basic structural unit of a myofibril

A

sarcomere consisting of a thin actin and thick myosin

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8
Q

what are the sleeves around the myofibril and what are their purpose

A

Sacrolemma and sarcoplasmic reticulum: sereve as Ca2+ storage and sleeves around each myofibril

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9
Q

what are Transverse tubules

A

(t-tubules) and they are invaginations of the sacrolemma

help with transmission of action potentials and regulating cellular calcium levels

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10
Q

Terminal cisternae

A

dilated ends of the sarcoplasmic reticulum and they release the Calcium to trigger the muscle contraction

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11
Q

Structure of a sarcomere: Z line

A

Anchor site for actin (thin) filaments

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12
Q

Structure of a sarcomere: I band

A

Only contains actin filaments

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13
Q

Structure of a sarcomere: M-line

A

Anchor site for thick myosin filaments

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14
Q

Structure of a sarcomere: H-zone

A

contains only thick myosin filaments

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15
Q

Structure of a sarcomere: A-band

A

overlap of thick and thin filaments plus the H-zone

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16
Q

Sliding filament mechanism

A

during muscle contraction:
the thin filaments slide past the thick filaments toward the center of the sarcomere
this brings the Z lines close together

every myofibril in a muscle cell shortens at the same time and thus the entire muscle contracts

The thin and thick filaments do not change length they just change the degree they overlap

17
Q

Tropomyosin

A

runs in the groove formed by F actin strands and it will bind to the troponin complex

18
Q

Troponin 3 types

A

Troponin T: Binds the complex to tropomyosin

Troponin I: inhibits the binding of myosin to actin

Troponin C: binds calcium

19
Q

Skeletal Muscle Fibers: Type I fibers

A

slow oxidative
contains slow ATPase, red due to high myoglobin
contractions slower and less powerful
contract for long periods of time without fatigue

20
Q

Skeletal Muscle Fibers: Type IIa fibers

A

Oxidative-glycolytic
largest and most prevalent
intermediate ATPase and provides power
Primarily aerobic - intermediate fatigue

21
Q

Skeletal Muscle Fibers: Type IIb fibers

A
Fast gycolytic
Fast ATPase produces fast contractions
largely anaerobic
rapid fatigue
lower myoglobin content
22
Q

Neuroglia

A

Neuron supporting cells

much smaller than the neuron

23
Q

Neuron

A

specialized for conduction of electrical impulses
cell body- process the electrical information
cell processes:
dendrites: carry electrical signal toward the nerve cell body
axon: 1 per cell and they carry the electrical signal away from the nerve cell

24
Q

Nissl substance

A

cluster of staining in the neurons that show the abundant rough endoplasmic reticulum that takes up the stain

reflects the need to make lots of neurotransmitters and protein to maintain the neuron

25
Q

3 classes of neurons

A

Multipolar: Many dendrites and one axon
Bipolar: one dendrite and one axon
Unipolar: one cell process from which branches a single axon and single dendrite

26
Q

how do schwann cells and satellite cells interact with the neuron

A

Satelitte cells surround the cell body of the neuron
Schwann cells surround the nerve fiber by wrapping its self around multiple times, even unmylinated fibers but just not as many times

27
Q

how does myelination help the transmission signal

A

creates nodes that allows for the signal to jump from node to node making the signal move much faster

28
Q

what are the three connective tissues that surround a peripheral nerve

A

Endoneurium: CT between axons
Perineurium: CT surrounding clusters of axons forming fascicles
Epineurium: CT surrounding several nerve fascicles

29
Q

What are the parts to the chemical synapse

A

Pre synaptic knob (axon terminal)
synaptic cleft
Pre synaptic membrane
Post synaptic membrane

30
Q

Neuromuscular junction

A

Every skeletal muscle cell recieves an axon terminal where they release the neurotransmitters

the neurotransmitter causes changes in the sarcolemma that excite the muscle
this travels down the T Tubules that initicat the fiber contraction at the terminal cisterna (release of calcium)

31
Q

Muscle spindle receptors:

A

monitor changes in length, rate of change, and tension of muscle
Intrafusal fibers: inside the muscle spindle
Extrafusal fibers: oustside the spindle, alpha motor fibers

32
Q

Intrafusal fibers:

A

Nuclear bag fibers: wraps near center of cell and detect changes in length and degree of tension, Type Ia

Nuclear chain fibers: wraps end of cell and detects static muscle length Type II

33
Q

Golgi tendon organs:

A

encapsulated receptors within myotendinous junctions that sense tension within the tendon