High level perception - Mirror neurons Flashcards

1
Q

How were mirror neurons discovered?

A

Found cells in the premotor and parietal regions of the macaque brain that fire both when performing and observing the same action.

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2
Q

where have MN been found in the brain monkey ?

A
  • originally found in the F5 (premotor cortex)
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3
Q

Neurons in the M1 do what

A

operate single muscles, the M1 is arranged so that neighbouring neurons activate neighbouring muscles

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4
Q

Premotor cortex

A
  • Goal-directed action
  • provides input to the M1
  • causes movement in groups of muscles
  • activity in one neuron can generate coordinated action
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5
Q

What do mirror neurons respond to?

A

They responded during the execution of a goal directed action like reaching or grasping and griping things.

They also respond to the site of other people performing goal directed actions.

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6
Q

Rizzollatti - looked at mirror neurons in monkeys

A

Object - precision grip - this cell responds to the site of the experimenter doing the action - when the monkey reaches out and gets the raisin there is also a motor neuron response.

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7
Q

Are mirror neurons action specific?

A

Mirror neurons respond during specific actions
Mirror neurons respond to the sight of the specific action
for example study found mirror neuron that only responded to an anti-clockwise motion

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8
Q

Face actions and mirror neurons

A

ome mirror neurons only respond to actions of the face.

  • Mirror neurons respond during movement of the face
  • Mirror neurons responded to the sight of face movements
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9
Q

in monkeys what are the different face actions mirror neurons respond to?

A

Ingestive: grasping, sucking

Communicative mouth actions: lip-smacking, teeth chatter

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10
Q

Do mirror neurons respond to Miming of actions?

A
  • they do not respond to the miming of actions the actions needs to actually occur for activity in the mirror neurons
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11
Q

do mirror neurons respond to hidden action?

A

Yes- they respond to the end of the action even if the action is out of sight
- but they have to have knowledge of the object being there - if they object is there

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12
Q

Occluder experiment

A

They know that the object is there but then it is covered and picked up and the mirror neurons react the motion because they know the outcome of the action but they do not do the same when there is no object there and they know this.

They MUST know the object is behind the occluder and they MUST see the hand disappearing behind it.

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13
Q

Superior Temporal Sulcus (STS)

A
  • neurons respond selectively to actions:

Moving faces, hands interacting with objects, walking

  • STS neurons integrate the sight and sound of actions
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14
Q

are mirror neurons in the STS

A

Despite looking, no-one has found mirror neurons in the STS, NOT YET

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15
Q

F5

A

responds to the sight and sound of actions and to motor behaviour - mirror neurons

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16
Q

PF

A

sight sound and motor

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17
Q

STS

A

The STS processes visual information related to biological motion, feeding this information to mirror neuron regions. (no motion does not have mirror neurons in itsself)

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18
Q

describe the mirror neuron system in the monkey

A

In monkeys, the mirror neuron system involves area F5 in the ventral premotor cortex, which receives input via the inferior parietal lobule from the superior temporal sulcus (STS)

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19
Q

where would human mirror neurons be?

A

If humans have mirror neurons they should be found in human premotor cortex and inferioir parietal lobe

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20
Q

What experiments have looked at human mirror neurons?

A

Transcranial Magnetic Stimulation (TMS)

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21
Q

what does TMS do, when it stimulates the motor cortex?

A

Transcranial Magnetic Stimulation (TMS) of human motor cortex (M1) causes Motor Evoked Potentials (MEPs) in muscles

MEPs provided metric of Motor system activity

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22
Q

How does the Primary Motor Cortex (M1) contribute to the mirror neuron system?

A

M1 executes motor commands and is influenced by the mirror neuron system when preparing for or imitating movements.

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23
Q

What is the function of the Inferior Parietal Lobule (IPL) in the mirror neuron system?

A

The IPL integrates action perception and execution, allowing us to understand the intentions behind observed actions.

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24
Q

what are MEPs?

A

MEPs are electrical signals recorded from muscles after stimulating the motor cortex (M1) with TMS. They indicate the excitability of the motor system.

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25
What does a larger MEP indicate?
A larger MEP suggests greater cortical excitability, meaning the motor system is more responsive.
26
What happens to MEPs when observing an action?
Observing an action can increase MEP amplitude, showing that the motor system is primed for movement (linked to mirror neurons).
27
How does TMS over M1 affect MEPs?
TMS can enhance or suppress MEPs depending on stimulation parameters, helping researchers study motor system function.
28
How does the brain simulate observed actions?
Superior Temporal Sulcus (STS): Processes the visual motion. Inferior Parietal Lobule (IPL) & Premotor Cortex: Understands and plans the action. Primary Motor Cortex (M1): Becomes more excitable, preparing for movement (↑ MEPs with TMS).
29
How do Motor Evoked Potentials (MEPs) change when observing an action?
Observation activates the motor system – Watching an action excites mirror neurons in the premotor cortex & inferior parietal lobule (IPL), priming movement. 🔹 TMS over M1 increases MEPs – If TMS is applied to the primary motor cortex (M1) while observing an action, MEPs in the corresponding muscles increase, showing that the motor system is more excitable. 🔹 More Excitable = More Likely to Move – This suggests the brain is preparing to imitate or respond to the observed action, even if no movement occurs.
30
what do TMS studies reveal?
TMS reveals that action observation directly influences motor excitability, supporting the role of the mirror neuron system in movement and learning.
31
How did the researchers use tongue molds in their study?
They created molds of participants' tongues to study the connection between tongue movement, sound perception, and motor responses.
32
What did Fadiga et al. (1999) find about hearing tongue-related sounds?
They found that hearing words with phonemes requiring tongue movements (like "t," "d," or "n") led to stronger MEP responses, suggesting auditory perception of these sounds activates the motor system. Listening to words that use the tongue enhance MEPs in the subject’s tongue
33
What is the key conclusion from Fadiga et al. (1999)? tongue study
The brain regions responsible for speech and motor actions are activated by hearing sounds that involve the tongue, demonstrating a connection between auditory perception and motor functions.
34
criticicms of the idea of humans having mirror neurons?
- some have argued humans don’t - evidence is indirect - relies on correlational between visual and motor activity - neuroimaging is a measure of correlation
35
what are single cell studys?
single-cell studies allow scientists to investigate how individual cells contribute to broader brain functions, giving a more detailed understanding of neural processes.
36
What evidence for human mirror neuron system has been found with single cell studies?
Found evidence for motor neurons in the Supplementary Motor Area and the Hippocampus. They were responding to both observation and executions of actions they responded to this and were more distributed
37
Why is neuroimaging evidence of mirror neurons considered correlational?
Neuroimaging shows an association between brain activity and behaviors (e.g., observing or performing actions), but it doesn't prove that mirror neurons cause the observed activity, only that certain brain regions are activated during these tasks.
38
How does single-cell evidence overcome the correlational issue of neuroimaging in mirror neuron research?
Single-cell studies directly measure the activity of individual neurons, providing causal evidence of their role in action observation and performance. This offers more specific proof that certain neurons are involved in behaviors, unlike neuroimaging, which only shows brain activity patterns without directly linking them to causality.
39
what are mirror neurons used for?
- action perception - touch - language - intention - understanding action
40
Observers walking on a treadmill: then had a person on a screen in front of them had to judge the biological motion walker and say what speed they were walking at. they had to do this stood still walking and cyclying. - who did worse?
People were less accurate at judging walking speed when they were cycling or standing still, compared to when they were walking. This shows that perception of others’ actions is enhanced when you're performing the same action, suggesting action-specific motor simulation in the brain.
41
Simulation Theory (Gallese & Goldman, 1998)
To understand other people’s actions we simulate their actions - using our motor systems
42
Theory Theory
*We acquire and deploy a commonsense theory of mind – set of causal/explanatory laws* **If our motor system is active when we observe other peoples actions - why don’t we automatically move. and what stops us moving.**
43
How do mirror neurons help us understand action?
1. When we execute an action – our Mirror Neuron System is active 2. We understand the action that we are executing (goals, intent etc.) 3. Perception of other people’s actions -> activity in mirror neuron system 4. Therefore: understand the action
44
What are mirror neurons for touch?
Mirror neurons for touch are somatosensory neurons that respond both during touch and when observing another person being touched.
45
How do somatosensory neurons code touch?
Different neurons code touch in different places, allowing you to empathize with the person being touched, but you don’t actually feel the touch yourself.
46
What role do mechanoreceptors play in touch perception?
Mechanoreceptors are pain receptors in the skin that provide feedback to the brain, signaling that you are not being touched.
47
What happens if nerve feedback is blocked, such as with a nerve block in the brachial plexus?
Blocking nerve feedback causes you to actually feel when someone else is touched and observe it, as the skin no longer provides the usual barrier between your own sensory experience and that of others.
48
mirror neurons and action intention
Greater activity in premotor cortex to intention condition Mirror neurons responsible for understanding the intention of the observed actor
49
What did Bucconio et al. (2004) find about brain activation when observing different stimuli?
They found greater brain activation when participants observed human lip-speaking and monkey lip-making compared to dog barking.
50
What does the greater brain activation for human lip-speaking suggest?
It suggests that humans more strongly process stimuli that are familiar or known to them, such as human speech.
51
What does the study by Bucconio et al. (2004) suggest about how humans process stimuli?
It suggests that humans tend to process more strongly stimuli that are relevant or familiar to them, like human speech or social cues, due to cognitive efficiency and evolutionary relevance.
52
what disorder shows deficits with mirror neurons?
ASD
53
ASD have less activation where?
negative correlation with activity in inferior frontal gryus (mirror system) and ASD and this leads to inability to do this task.
54
What do mirror neurons represent in terms of actions?
Mirror neurons represent actions, allowing for both imitation and understanding of actions, linking the sender (actor) and receiver (observer).
55
What does Liberman’s Motor Theory of Speech (1993) suggest about communication?
It suggests that communication relies on the same motor system used for actions, where mirror neurons help us understand speech as an action and imitate mouth movements.
56
What is the relationship between the F5 region in monkeys and Broca’s area in humans?
The F5 region in monkeys, which controls hand and mouth movements, is the homologue of Broca’s area in humans, which is responsible for speech production.
57
What did Arbib & Rizzolatti (2001) suggest about mirror neurons and communication?
They suggested that: Observers recognize actions and intentions through mirror neurons. Conscious control of the mirror system allows for voluntary signals. A primitive dialogue begins between the observer and the actor, starting with non-verbal gestures.
58
What role did mirror neurons play in early communication?
Mirror neurons helped form primitive dialogue using hand movements, and later mouth movements (oro-facial gestures), which may have been the precursor to language.
59
Did language evolve from the use of hand movements and the mirror neuron system?
It's suggested that language could have evolved from hand gestures and the mirror neuron system, building on early non-verbal communication.
60
How does the mirror neuron system in humans differ from non-human primates?
The human mirror neuron system may be more complex, supporting advanced communication (like speech) and cognitive abilities, while non-human primates may focus more on action recognition and imitation.
61
What does Mu rhythm suppression indicate in terms of motor activation?
Mu rhythm suppression is an index of motor activation that occurs when we observe actions. It is a key marker of mirror neuron activity.
62
What is the Mu rhythm suppression finding in individuals with ASD?
Individuals with ASD show reduced Mu rhythm suppression during action observation, suggesting impaired mirror neuron system activity.
63
What does TMS-induced corticospinal activation measure?
TMS-induced corticospinal activation measures motor system activity during action observation, specifically testing mirror neuron function.
64
What was found about TMS-induced corticospinal activation in individuals with ASD?
Reduced corticospinal activation during action observation was found in individuals with ASD, suggesting impaired mirror neuron system performance.
65
What did studies show about MNS response in children with ASD?
Children with ASD show reduced MNS response to both observation and execution of facial expressions, indicating dysfunction in the Mirror Neuron System. The response is specifically reduced in the Inferior Frontal Gyrus (IFG).
66
reduced mu rhythm supression means
leading to difficulties in action understanding, imitation, empathy, and social interaction (being able to recognise others emotion.
67
What did Hamilton (2004) find about how action execution affects perception?
Participants judged the weight of objects lifted by others while lifting objects themselves. Lifting a heavy object → others' object appeared lighter. Lifting a light object → others' object appeared heavier. 🧠 Suggests that your own motor state biases how you perceive others' actions. Supports the role of the mirror neuron system in action simulation and perception-action coupling.