HF/Diuretics Flashcards
B-type Natriuretic peptides mechanism of action
Diuresis, natriuresis, vasodilating effects on arteries and veins, indirectly increases CO, indirectly suppresses RAAS
Nesiritide classification
B-type Natriuretic peptides
Nesiritide adverse effects
HYPOtension, dysrhythmia, headache, abdominal pain, insomnia
Nesiritide use
Synthetic, used in ICU as last resort to treat severe HF
Loop Diuretics mechanism of action
Act directly on the ascending limb of the loop of Henle, inhibits chloride and sodium reabsorption.
Loop diuretics examples
Furosemide, bumetanide, torsemide.
Loop diuretics effects
Potent diuresis and subsequent loss of fluid, decreases fluid volume, K+/salt depletion.
Loop diuretics indications
Acute CHF, acute edema, HTN, hypercalcemia
loop diuretics adv effects:
HYPERGLYCEMIA, tinnitus, N/V, STEVENS-JOHNSON (torsemide)
loop diuretics considerations:
check BUN/Creatinine, kidney toxic, neurotoxic
loop diuretics contraindications:
allergy, electrolyte depletion, anuria, severe renal failure, liver coma, preg/lactating
loop diuretics interactions:
-thizadide
-anticoagulants
-NSAIDS
